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Study · Not a test of the peptide alone · 2019

2 results

The Mechanism of Action of Ghrelin and Motilin in the Pacemaker Potentials of Interstitial Cells of Cajal from the Murine Small Intestine.

Kim JN, Kim BJ

Molecules and cells1 Jun 2019Cited by 12 (Europe PMC)

PMID31250620 (opens in a new tab)PMCIDPMC6602145 (opens in a new tab)DOI10.14348/molcells.2019.0028 (opens in a new tab)PepBankPUB-31250620
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01LabNot a test of GHRP-6 aloneIn vitro (cells)Mechanism

    In cultured mouse interstitial cells of Cajal, D-Lys-GHRP‑6 completely inhibited ghrelin-induced pacemaker depolarization.

    In plain wordsIn cells from mouse intestine, D-Lys-GHRP‑6 completely blocked pacemaker depolarization compared with ghrelin alone.

    Peptide
    GHRP-6
    Outcome
    DecreaseGhrelin-induced pacemaker depolarization
    Study

    mousen: not reported in source

    cultured interstitial cells of Cajal from small intestine
    Comparator
    Ghrelin alone
    Outcome group
    Receptor activity and mechanism · Gastrointestinal

    Source sentences

    Summary
    The ghrelin receptor antagonist [D-Lys] GHRP-6 completely inhibited this ghrelin-induced depolarization.
    1 context sentence
    Summary · context
    In this study, we investigated the effects of ghrelin and motilin on the pacemaker potentials of ICCs isolated from the mouse small intestine.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02LabNot a test of GHRP-6 aloneIn vitro (cells)Mechanism

    In cultured mouse interstitial cells of Cajal, D-Lys-GHRP‑6 completely inhibited motilin-induced pacemaker depolarization.

    In plain wordsIn cells from mouse intestine, D-Lys-GHRP‑6 completely blocked pacemaker depolarization compared with motilin alone.

    Peptide
    GHRP-6
    Outcome
    DecreaseMotilin-induced pacemaker depolarization
    Study

    mousen: not reported in source

    cultured interstitial cells of Cajal from small intestine
    Comparator
    Motilin alone
    Outcome group
    Receptor activity and mechanism · Gastrointestinal

    Source sentences

    Summary
    In addition, motilin depolarized the pacemaker potentials of ICCs in a similar dose-dependent manner as ghrelin, and this was also completely inhibited by [D-Lys] GHRP-6.
    1 context sentence
    Summary · context
    In this study, we investigated the effects of ghrelin and motilin on the pacemaker potentials of ICCs isolated from the mouse small intestine.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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