Skip to content

Study · Animal study (in vivo) · rat · 2019

2 results

State of Colon Microbiota in Rats during Chronic Restraint Stress and Selank Treatment.

Mukhina AY, Medvedeva OA, Svishcheva MV, Shevchenko AV, Efremova NN, Bobyntsev II, Kalutskii PV, Andreeva LA, Myasoedov NF

Bulletin of experimental biology and medicine24 Jun 2019Cited by 5 (Europe PMC)

PMID31236882 (opens in a new tab)DOI10.1007/s10517-019-04496-y (opens in a new tab)PepBankPUB-31236882
Source linkPubMedAsk about this study
Jump to 2 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats under chronic restraint stress, Selank restored the colon microbiota, which stress had reduced in obligate microflora.

    In plain wordsIn rats under chronic restraint stress, Selank restored the gut bacteria that stress had reduced.

    Peptide
    Selank
    Outcome
    IncreaseObligate colon microflora
    Study

    ratn: not reported in source

    Chronic restraint stress in Wistar male rats
    Outcome group
    Gut microbiota · Gastrointestinal
    Studied dose
    80, 250 and 750 μg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Selank restored intestinal microbiota
    3 context sentences
    Summary · context
    Chronic restraint stress led to a decrease in the content of obligate microflora, while the content of opportunistic microorganisms increased.
    Summary · context
    We studied the effects of Selank on intestinal microbiota in Wistar male rats subjected to chronic restraint stress.
    Summary · context
    Selank was injected intraperitoneally in doses of 80, 250 and 750 μg/kg 15 min before stress exposure.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats under chronic restraint stress, Selank restored the colon microbiota, which stress had shifted toward more opportunistic microorganisms.

    In plain wordsIn rats under chronic restraint stress, Selank restored the gut balance that stress had shifted toward opportunistic microbes.

    Peptide
    Selank
    Outcome
    DecreaseOpportunistic colon microorganisms
    Study

    ratn: not reported in source

    Chronic restraint stress in Wistar male rats
    Outcome group
    Gut microbiota · Gastrointestinal
    Studied dose
    80, 250 and 750 μg/kg · intraperitonealAs given in this study (rat).

    Source sentences

    Summary
    Selank restored intestinal microbiota
    3 context sentences
    Summary · context
    Chronic restraint stress led to a decrease in the content of obligate microflora, while the content of opportunistic microorganisms increased.
    Summary · context
    We studied the effects of Selank on intestinal microbiota in Wistar male rats subjected to chronic restraint stress.
    Summary · context
    Selank was injected intraperitoneally in doses of 80, 250 and 750 μg/kg 15 min before stress exposure.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.