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Study · Not a test of the peptide alone · 2019

1 result

Treatment of Multidrug-Resistant Vancomycin-Resistant Enterococcus faecium Hardware-Associated Vertebral Osteomyelitis with Oritavancin plus Ampicillin.

Dahesh S, Wong B, Nizet V, Sakoulas G, Tran TT, Aitken SL

Antimicrobial agents and chemotherapy24 Jun 2019Cited by 22 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking LL-37.

  1. 01LabNot a test of LL-37 aloneIn vitro (cells)Activity measurement

    In lab tests, the combination of oritavancin and ampicillin showed further synergy with the human antimicrobial peptide LL‑37.

    In plain wordsIn lab tests, the antibiotic pair oritavancin and ampicillin worked even better together with LL‑37.

    Peptide
    LL-37
    Outcome
    Not applicableSynergy of oritavancin plus ampicillin with LL-37
    Study

    Enterococcus faeciumn: not reported in source

    Vancomycin-resistant E. faecium isolate
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    Further synergies of oritavancin and ampicillin with rifampin or the endogenous human antimicrobial peptide cathelicidin LL-37 were demonstrated.
    1 context sentence
    Summary · context
    Weekly oritavancin plus ampicillin continuous infusion combination therapy was used to successfully treat a deep spine vancomycin-resistant Enterococcus faecium infection associated with hardware.

    In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking LL-37.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:57 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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