A systematic review found significant correlations between the body's own LL‑37 level in oral fluids or tissues and clinical periodontal indexes (PD, CAL) and/or bacteriological index.
In plain wordsStudies linked higher or lower natural LL‑37 levels in the mouth to measures of gum disease; the direction is not stated.
- Peptide
- LL-37
- Outcome
- Direction not reportedAssociation of LL-37 level with periodontal indexes
- Study
n: not reported in source
- Outcome group
- Inflammation markers · Immune and inflammation
Source sentences
Significant correlations between clinical periodontal indexes (PD, CAL) and/or bacteriological index and LL37 level were retrieved.
1 context sentence(design, population, supporting numbers)
Only clinical studies that focused on assays of the expression and/or production of AMPs in human adult oral fluids (gingival crevicular fluid or saliva) or in oral tissues were retained and finally seventy-four publications meeting inclusion criteria were included.
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.