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Study · Observational study · n = 112 · 2019

4 results

Short-term daily teriparatide improve postoperative functional outcome and fracture healing in unstable intertrochanteric fractures.

Kim SJ, Park HS, Lee DW, Lee JW

Injury3 Jun 2019Cited by 38 (Europe PMC)

PMID31182230 (opens in a new tab)DOI10.1016/j.injury.2019.06.002 (opens in a new tab)PepBankPUB-31182230
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanObservational studyEfficacy outcome

    In patients with unstable intertrochanteric fractures, teriparatide use was linked to higher Harris hip scores than fixation alone.

    In plain wordsIn patients with hip fractures, teriparatide use was linked to better hip scores than fixation alone.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    IncreaseHarris hip score
    Study

    n = 112

    Comparator
    Proximal femoral nail alone
    Outcome group
    Exercise and physical function · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneousAs given in this study (human).

    Source sentences

    Summary
    Teriparatide therapy significantly increased HHS (p = 0.02) and decreased VAS pain scores (p = 0.008).
    2 context sentences
    Summary · context
    Between 2014 and 2017, we retrospectively assessed 112 patients who underwent closed reduction and internal fixation with proximal femoral nail (PFN) for unstable intertrochanteric fractures.
    Summary · context
    These patients were compared with 52 patients for whom the same device was used and a daily subcutaneous injection of teriparatide (1-34 PTH, Forsteo®) was prescribed postoperatively (group II).
  2. 02HumanObservational studyEfficacy outcome

    In patients with unstable intertrochanteric fractures, teriparatide use was linked to lower pain scores than fixation alone.

    In plain wordsIn patients with hip fractures, teriparatide use was linked to lower pain scores than fixation alone.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    DecreaseVAS pain score
    Study

    n = 112

    Comparator
    Proximal femoral nail alone
    Outcome group
    Pain · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneousAs given in this study (human).

    Source sentences

    Summary
    Teriparatide therapy significantly increased HHS (p = 0.02) and decreased VAS pain scores (p = 0.008).
    2 context sentences
    Summary · context
    Between 2014 and 2017, we retrospectively assessed 112 patients who underwent closed reduction and internal fixation with proximal femoral nail (PFN) for unstable intertrochanteric fractures.
    Summary · context
    These patients were compared with 52 patients for whom the same device was used and a daily subcutaneous injection of teriparatide (1-34 PTH, Forsteo®) was prescribed postoperatively (group II).
  3. 03HumanObservational studyEfficacy outcome

    In patients with unstable intertrochanteric fractures, teriparatide use was linked to shorter healing time than fixation alone.

    In plain wordsIn patients with hip fractures, teriparatide use was linked to faster healing than fixation alone.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    DecreaseTime to fracture healing
    Study

    n = 112

    Comparator
    Proximal femoral nail alone
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneousAs given in this study (human).

    Measurements

    Healing time
    12.1 weeks
    teriparatide
    Healing time
    14.8 weeks
    fixation alone

    Source sentences

    Summary
    The mean time to fracture healing post-operatively was 14.8 weeks (SD 7.1) and 12.1 weeks (SD 6.4) in group I and II, respectively (p = 0.002).
    2 context sentences
    Summary · context
    Between 2014 and 2017, we retrospectively assessed 112 patients who underwent closed reduction and internal fixation with proximal femoral nail (PFN) for unstable intertrochanteric fractures.
    Summary · context
    These patients were compared with 52 patients for whom the same device was used and a daily subcutaneous injection of teriparatide (1-34 PTH, Forsteo®) was prescribed postoperatively (group II).
  4. 04HumanObservational studySafety outcome

    In patients with unstable intertrochanteric fractures, teriparatide use was linked to fewer postoperative complications than fixation alone.

    In plain wordsIn patients with hip fractures, teriparatide use was linked to fewer postoperative complications than fixation alone.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    DecreasePostoperative complications
    Study

    n = 112

    Comparator
    Proximal femoral nail alone
    Outcome group
    Adverse events · Musculoskeletal
    Studied dose
    Dose not stated · subcutaneousAs given in this study (human).

    Source sentences

    Summary
    The frequency of patients reporting postoperative complications was also markedly reduced in the teriparatide-treated groups (p = 0.028).
    2 context sentences
    Summary · context
    Between 2014 and 2017, we retrospectively assessed 112 patients who underwent closed reduction and internal fixation with proximal femoral nail (PFN) for unstable intertrochanteric fractures.
    Summary · context
    These patients were compared with 52 patients for whom the same device was used and a daily subcutaneous injection of teriparatide (1-34 PTH, Forsteo®) was prescribed postoperatively (group II).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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