In rats with acoustic trauma given intratympanic oxytocin, auditory brainstem response thresholds rose on day 1, with no significant difference from baseline on days 7 and 21.
In plain wordsIn rats with noise injury given oxytocin in the ear, hearing thresholds rose on day 1 and were back near baseline by day 7.
- Peptide
- Oxytocin
- Outcome
- MixedAuditory brainstem response thresholds after acoustic trauma
- Study
ratn: not reported in source
- Comparator
- Baseline before acoustic trauma
- Outcome group
- Sensory perception · Nervous system and cognition
- Studied dose
- Dose not stated · intratympanic · Days 1 to 10 (doses on days 1, 2, 4, 6, 8 and 10)As given in this study (rat).
Source sentences
In group 3, auditory brainstem response thresholds increased significantly on day 1 after acoustic trauma, but there were no significant differences between thresholds at baseline and on the 7th and 21st days.
1 context sentence(design, population, supporting numbers)
Twenty-eight rats were divided into four groups: noise (group 1), control (group 2), noise plus oxytocin (group 3), and oxytocin (group 4). Intratympanic oxytocin was administered on days 1, 2, 4, 6, 8 and 10 in groups 3 and 4. Groups 1 and 3 were exposed to acoustic trauma.