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Study · Animal study (in vivo) · horse · 2019

3 results

Using Estrous Behavior to Time Initiation of Oxytocin Administration to Prolong Luteal Function in Mares.

Manning HS, Runcan EE, Dias de Moraes CR, Coutinho da Silva MA

Journal of equine veterinary science6 Feb 2019

PMID31002098 (opens in a new tab)DOI10.1016/j.jevs.2019.01.012 (opens in a new tab)PepBankPUB-31002098
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mares, once-daily oxytocin from Day 8 lengthened the average interestrus interval versus untreated controls (32.4 vs 21.8 days, P = .01).

    In plain wordsIn mares, daily oxytocin lengthened the time between heats compared with no treatment.

    Peptide
    Oxytocin
    Outcome
    IncreaseAverage interestrus interval
    Study

    horsen = 23

    light breed mares
    Comparator
    Untreated control
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    60 IU once daily · intramuscular · Day 8 to Day 17 after onset of estrusAs given in this study (horse).

    Measurements

    interestrus interval
    32.4 days
    oxytocin
    interestrus interval
    21.8 days
    control

    Source sentences

    Summary
    The average interestrus interval was higher for treated mares compared with control mares (32.4 ± 4.2 vs. 21.8 ± 1.5 days, respectively, P = .01).
    2 context sentences
    Summary · context
    Twenty-three light breed mares (aged 4-20 years) were exposed to a stallion and observed for signs of sexual receptivity.
    Summary · context
    On the day that estrous behavior was observed (Day 0), mares were randomly divided into two groups: oxytocin (n = 11): oxytocin (60 IU, IM) was administered once daily from Day 8-17; control (n = 12): did not receive treatment.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In the oxytocin group, 6 of 11 mares (54.5%) had an interestrus interval longer than 31 days.

    In plain wordsIn mares given oxytocin, 6 of 11 had a heat interval longer than 31 days.

    Peptide
    Oxytocin
    Outcome
    Not applicableMares with interestrus interval longer than 31 days
    Study

    horsen = 11

    light breed mares
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    60 IU once daily · intramuscular · Day 8 to Day 17 after onset of estrusAs given in this study (horse).

    Measurements

    mares with interval >31 days
    54.5%
    oxytocin group

    Source sentences

    Summary
    In the oxytocin group, the interestrus interval was longer than 31 days in 6 of 11 (54.5%) mares
    2 context sentences
    Summary · context
    Twenty-three light breed mares (aged 4-20 years) were exposed to a stallion and observed for signs of sexual receptivity.
    Summary · context
    On the day that estrous behavior was observed (Day 0), mares were randomly divided into two groups: oxytocin (n = 11): oxytocin (60 IU, IM) was administered once daily from Day 8-17; control (n = 12): did not receive treatment.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In the oxytocin group, 5 of 11 mares (45.5%) had an interestrus interval of up to 45 days.

    In plain wordsIn mares given oxytocin, 5 of 11 had a heat interval of up to 45 days.

    Peptide
    Oxytocin
    Outcome
    Not applicableMares with interestrus interval up to 45 days
    Study

    horsen = 11

    light breed mares
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    60 IU once daily · intramuscular · Day 8 to Day 17 after onset of estrusAs given in this study (horse).

    Measurements

    mares with interval up to 45 days
    45.5%
    oxytocin group

    Source sentences

    Summary
    up to 45 days in 5 of 11 mares (45.5%).
    2 context sentences
    Summary · context
    Twenty-three light breed mares (aged 4-20 years) were exposed to a stallion and observed for signs of sexual receptivity.
    Summary · context
    On the day that estrous behavior was observed (Day 0), mares were randomly divided into two groups: oxytocin (n = 11): oxytocin (60 IU, IM) was administered once daily from Day 8-17; control (n = 12): did not receive treatment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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