Skip to content

Study · Animal study (in vivo) · rat · 2019

3 results

Cerebrolysin improves peripheral inflammatory pain: Sex differences in two models of acute and chronic mechanical hypersensitivity.

Morales-Medina JC, Flores G, Vallelunga A, Griffiths NH, Iannitti T

Drug development research25 Mar 2019Cited by 17 (Europe PMC)

PMID30908710 (opens in a new tab)DOI10.1002/ddr.21528 (opens in a new tab)PepBankPUB-30908710
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In male and female CFA-treated rats, cerebrolysin reversed mechanical allodynia.

    In plain wordsIn male and female rats with CFA-induced inflammation, cerebrolysin reduced sensitivity to mechanical pain.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseMechanical allodynia
    Study

    ratn: not reported in source

    CFA-induced peripheral inflammation, both sexes
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cerebrolysin reversed the mechanical allodynia in both sexes in CFA-treated rats.
    1 context sentence
    Summary · context
    We utilized the complete Freund's adjuvant (CFA) that produces maximal oedema and mechanical allodynia within days and carrageenan that produces similar effects within hours.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In female carrageenan-treated rats, cerebrolysin reduced mechanical allodynia.

    In plain wordsIn female rats with carrageenan-induced inflammation, cerebrolysin reduced sensitivity to mechanical pain.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseMechanical allodynia
    Study

    ratn: not reported in source

    Carrageenan-induced peripheral inflammation, female rats
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    On the other hand, in rats treated with carrageenan, cerebrolysin was only effective in reducing mechanical allodynia in female rats.
    1 context sentence
    Summary · context
    We utilized the complete Freund's adjuvant (CFA) that produces maximal oedema and mechanical allodynia within days and carrageenan that produces similar effects within hours.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In male carrageenan-treated rats, cerebrolysin was not effective in reducing mechanical allodynia.

    In plain wordsIn male rats with carrageenan-induced inflammation, cerebrolysin did not reduce sensitivity to mechanical pain.

    Peptide
    Cerebrolysin
    Outcome
    Direction not reportedMechanical allodynia
    Study

    ratn: not reported in source

    Carrageenan-induced peripheral inflammation, male rats
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    On the other hand, in rats treated with carrageenan, cerebrolysin was only effective in reducing mechanical allodynia in female rats.
    1 context sentence
    Summary · context
    We utilized the complete Freund's adjuvant (CFA) that produces maximal oedema and mechanical allodynia within days and carrageenan that produces similar effects within hours.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.