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Study · Animal study (in vivo) · rat · 2019

2 results

The induced decrease in TLR2 and TLR4 by cerebrolysin in the alcoholic liver of rats.

Mahmoudi J, Mahmoodpoor A, Amirnia M, Kazemi T, Chokhachi Baradaran P, Sheikh Najafi S, Sadigh-Eteghad S, Farajdokht F, Xu H, Belalzadeh M, Sandoghchian Shotorbani S

Journal of cellular physiology12 Feb 2019Cited by 7 (Europe PMC)

PMID30756376 (opens in a new tab)DOI10.1002/jcp.28293 (opens in a new tab)PepBankPUB-30756376
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats with alcoholic liver disease, a mild dose of cerebrolysin significantly decreased TLR2 expression versus other groups.

    In plain wordsIn rats with alcoholic liver disease, cerebrolysin reduced TLR2 expression compared with other groups.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseTLR2 expression
    Study

    ratn: not reported in source

    Alcoholic liver disease
    Comparator
    Other groups
    Outcome group
    Inflammation markers · Liver
    Studied dose
    mild doseAs given in this study (rat).

    Source sentences

    Summary
    The results of the present study showed that in mild dose of cerebrolysin, the expression of TLR2 and TLR4 was decreased significantly than other groups.
    2 context sentences
    Summary · context
    Also, the results of the western blot analysis proved the same.
    Summary · context
    TLR2 and TLR4 expressions were determined using real-time polymerase chain reaction in rats, which have used alcohol and they were separated into five groups.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats with alcoholic liver disease, a mild dose of cerebrolysin significantly decreased TLR4 expression versus other groups.

    In plain wordsIn rats with alcoholic liver disease, cerebrolysin reduced TLR4 expression compared with other groups.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseTLR4 expression
    Study

    ratn: not reported in source

    Alcoholic liver disease
    Comparator
    Other groups
    Outcome group
    Inflammation markers · Liver
    Studied dose
    mild doseAs given in this study (rat).

    Source sentences

    Summary
    The results of the present study showed that in mild dose of cerebrolysin, the expression of TLR2 and TLR4 was decreased significantly than other groups.
    2 context sentences
    Summary · context
    Also, the results of the western blot analysis proved the same.
    Summary · context
    TLR2 and TLR4 expressions were determined using real-time polymerase chain reaction in rats, which have used alcohol and they were separated into five groups.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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