In one small study of avulsed and replanted permanent teeth, soaking and injecting with thymosin α1 gave some evidence of better periodontal healing than saline (very low quality evidence).
In plain wordsIn one small study of knocked-out teeth, thymosin α1 gave some sign of better gum healing than saline; the evidence is very weak.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreasePeriodontal healing after tooth replantation
- Study
n = 73
- Comparator
- Saline
- Outcome group
- Wound healing · Skin and wound
- Studied dose
- Dose not stated · 10-minute soak before replantation, then daily gingival injections · 7 daysAs given in this study (human).
Source sentences
There was some evidence of a benefit for thymosin alpha 1 with respect to periodontal healing and tooth survival.
1 context sentence(design, population, supporting numbers)
The fourth study at high risk of bias with 73 participants compared a 10-minute soak in either thymosin alpha 1 or saline before replantation followed by daily gingival injections with these same medicaments for the first 7 days.