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Study · In vitro (cells) · rat · 2019

1 result

Resveratrol protects against isoproterenol induced myocardial infarction in rats through VEGF-B/AMPK/eNOS/NO signalling pathway.

Feng L, Ren J, Li Y, Yang G, Kang L, Zhang S, Ma C, Li J, Liu J, Yang L, Qi Z

Free radical research9 Jan 2019Cited by 54 (Europe PMC)

PMID30526144 (opens in a new tab)DOI10.1080/10715762.2018.1554901 (opens in a new tab)PepBankPUB-30526144
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In neonatal rat ventricular myocytes, AICAR rescued the effect of VEGF-B knockdown on eNOS activation in the resveratrol experiment.

    In plain wordsIn rat heart cells, AICAR restored eNOS activation affected by VEGF-B knockdown in the resveratrol experiment.

    Peptide
    AICAR (acadesine)
    Outcome
    IncreaseeNOS activation rescue
    Study

    ratn: not reported in source

    Neonatal rat ventricular myocytes
    Outcome group
    Receptor activity and mechanism · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Meantime, we found that the effect of VEGF-B knock-down on eNOS activation was rescued by AMPK activator AICAR.
    2 context sentences
    Summary · context
    Using Neonatal Rat Ventricular Myocytes (NRVM), we found that VEGF-B siRNA could abolish the cardio-protective effect of RSV.
    Summary · context
    The enhanced ratios of eNOS phosphorylation to eNOS expression induced by RSV were markedly reversed by VEGF-B siRNA in NRVM also.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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