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Study · Observational study · n = 47 · 2019

2 results

Effect of Teriparatide on Subsequent Vertebral Fractures after Instrumented Fusion Surgery for Osteoporotic Vertebral Fractures with Neurological Deficits.

Maruo K, Tachibana T, Arizumi F, Kusuyama K, Kishima K, Yoshiya S

Asian spine journal29 Nov 2018Cited by 20 (Europe PMC)

PMID30481980 (opens in a new tab)PMCIDPMC6454279 (opens in a new tab)DOI10.31616/asj.2018.0098 (opens in a new tab)PepBankPUB-30481980
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanObservational studyEfficacy outcome

    After instrumented fusion for osteoporotic vertebral fractures, subsequent fractures occurred in 16% with teriparatide versus 54% without it.

    In plain wordsAfter spinal fusion for osteoporotic fractures, teriparatide was linked to fewer subsequent vertebral fractures than no teriparatide.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    DecreaseSubsequent vertebral fracture incidence
    Study

    n = 47

    Comparator
    No teriparatide
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Measurements

    Subsequent vertebral fracture incidence
    16%
    teriparatide group
    Subsequent vertebral fracture incidence
    54%
    non-teriparatide group

    Source sentences

    Summary
    The occurrence of subsequent VFs was lower in the TP group than in the non-TP group (16% vs. 54%, p=0.014).
    3 context sentences
    Summary · context
    Retrospective case review.
    Summary · context
    Overall, 47 patients who underwent long-instrumented fusion surgery (≥3 levels) for OVFs with neurological deficits between 2010 and 2013 were enrolled.
    Summary · context
    TP was used for 19 patients who comprised the TP group.
  2. 02HumanObservational studyEfficacy outcome

    After instrumented fusion for osteoporotic vertebral fractures, preoperative teriparatide was associated with lower subsequent fracture hazard in the Cox model.

    In plain wordsAfter spinal fusion for osteoporotic fractures, preoperative teriparatide was linked to lower subsequent fracture hazard than no teriparatide.

    Peptide
    Teriparatide (PTH 1-34)
    Outcome
    DecreaseAdjusted subsequent vertebral fracture hazard
    Study

    n = 47

    Comparator
    No teriparatide
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    Dose not stated

    Measurements

    Hazard ratio
    0.281 ratio
    preoperative teriparatide in Cox model

    Source sentences

    Summary
    A Cox proportional hazards model revealed that preoperative TP treatment is only a protective factor of subsequent VFs after instrumented fusion surgery for OVFs (hazard ratio, 0.281; p=0.047).
    3 context sentences
    Summary · context
    Retrospective case review.
    Summary · context
    Overall, 47 patients who underwent long-instrumented fusion surgery (≥3 levels) for OVFs with neurological deficits between 2010 and 2013 were enrolled.
    Summary · context
    TP was used for 19 patients who comprised the TP group.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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