In MH7A synovial cells, D-Lys-GHRP‑6 significantly reversed ghrelin-induced apoptotic effects.
In plain wordsIn cells, D-Lys-GHRP‑6 reduced the apoptotic effects of ghrelin compared with ghrelin stimulation.
- Peptide
- GHRP-6
- Outcome
- DecreaseGhrelin-induced apoptosis
- Study
n: not reported in source
MH7A synovial cells- Comparator
- Ghrelin stimulation
- Outcome group
- Receptor activity and mechanism · Musculoskeletal
Source sentences
Then these apoptotic effects were significantly reversed by [D-Lys3] GHRP-6 (ghrelin receptor antagonist).
2 context sentences(design, population, supporting numbers)
The results of flow cytometry and TUNEL showed that ghrelin could induce apoptosis of MH7A synovial cells.
Therefore, the aim of this study is to explore the apoptotic effects of ghrelin on MH7A synovial cells in vitro.
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.