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Study · Randomized controlled trial · 2019

2 results

Oxytocin infusion reduces bleeding during abdominal myomectomies: a randomized controlled trial.

Aslan Çetin B, Aydoğan Mathyk B, Köroğlu N, Soydar A, Demirayak G, Çift T

Archives of gynecology and obstetrics17 Oct 2018Cited by 4 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients undergoing abdominal myomectomy, oxytocin infusion gave a mean intraoperative blood loss of 489.20 ml versus 641.40 ml with saline.

    In plain wordsIn women having fibroid surgery, an oxytocin drip was linked to less blood loss than a saline drip.

    Peptide
    Oxytocin
    Outcome
    DecreaseIntraoperative blood loss
    Study

    n: not reported in source

    Comparator
    Saline
    Analysis
    Primary
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    10 IU in 500 ml saline at 120 ml/h · intravenous · during the operationAs given in this study (human).

    Measurements

    Intraoperative blood loss
    489.2 ml
    oxytocin group
    Intraoperative blood loss
    641.4 ml
    control group

    Source sentences

    Summary
    The mean intraoperative blood loss during the surgery was 489.20 ± 239.72 ml in the oxytocin group and was 641.40 ± 288.21 ml in the control group.
    3 context sentences
    Summary · context
    The use of oxytocin infusion during the myomectomy resulted in a reduction of bleeding in the regression model.
    Summary · context
    Patients undergoing abdominal myomectomies were randomized 1:1 either to the oxytocin group or to the control group (saline).
    Summary · context
    In the oxytocin group, 10 IU oxytocin in 500 ml of saline at a rate of 120 ml/h was given during the course of the operation.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients undergoing abdominal myomectomy, the hemoglobin decline was smaller with oxytocin infusion than with saline.

    In plain wordsIn women having fibroid surgery, the blood count fell less with an oxytocin drip than with a saline drip.

    Peptide
    Oxytocin
    Outcome
    DecreaseHemoglobin decline
    Study

    n: not reported in source

    Comparator
    Saline
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    10 IU in 500 ml saline at 120 ml/h · intravenous · during the operationAs given in this study (human).

    Source sentences

    Summary
    The hemoglobin decline was more evident in the control group than in the oxytocin group.
    2 context sentences
    Summary · context
    Patients undergoing abdominal myomectomies were randomized 1:1 either to the oxytocin group or to the control group (saline).
    Summary · context
    In the oxytocin group, 10 IU oxytocin in 500 ml of saline at a rate of 120 ml/h was given during the course of the operation.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:48 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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