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Study · Randomized controlled trial · n = 118 · 2019

2 results

Intranasal oxytocin does not alter initial perceptions of facial trustworthiness in younger or older adults.

Grainger SA, Henry JD, Steinvik HR, Vanman EJ

Journal of psychopharmacology (Oxford, England)17 Oct 2018Cited by 13 (Europe PMC)

PMID30326770 (opens in a new tab)DOI10.1177/0269881118806303 (opens in a new tab)PepBankPUB-30326770
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In younger and older adults, intranasal oxytocin had no effect on judgments of facial trustworthiness versus placebo.

    In plain wordsIn younger and older adults, oxytocin spray did not change how trustworthy faces looked, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeJudgments of facial trustworthiness
    Study

    n = 118

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, most critically, iOT had no effect on these judgments for either age group.
    1 context sentence
    Summary · context
    One hundred and eighteen participants took part in a randomized, double-blind, placebo-controlled, within-groups study.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In younger and older adults, intranasal oxytocin had no effect on eye gaze while judging faces versus placebo.

    In plain wordsIn younger and older adults, oxytocin spray did not change where people looked on faces, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEye gaze patterns
    Study

    n = 118

    Comparator
    Placebo
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, iOT had no effect on eye gaze.
    1 context sentence
    Summary · context
    One hundred and eighteen participants took part in a randomized, double-blind, placebo-controlled, within-groups study.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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