In healthy adults, the cortisol increment was higher after afternoon versus morning cosyntropin testing (11.89±3.50 versus 7.71±3.12 μg/dL, P=0.002).
In plain wordsIn healthy adults, afternoon cosyntropin testing increased cortisol from baseline more than morning testing.
- Peptide
- Cosyntropin
- Outcome
- IncreaseSerum cortisol increment at 30 minutes
- Study
n = 13
- Comparator
- Morning low-dose cosyntropin test
- Outcome group
- Adrenal Diagnostic Testing · Endocrine and hormones
Measurements
- Mean absolute serum cortisol increment, baseline to 30 minutes
- 11.89 μg/dL
- afternoon low-dose test, ±3.50 as reported
- Mean absolute serum cortisol increment, baseline to 30 minutes
- 7.71 μg/dL
- morning low-dose test, ±3.12 as reported
Source sentences
however, mean absolute SC-concentration increment between baseline and 30-minute time point was higher in the afternoon than in the morning (11.89±3.50 and 7.71±3.12 μg/dL, respectively; P=0.002).
3 context sentences(design, population, supporting numbers)
The current study was designed to investigate this prediction by comparing morning and afternoon cortisol responses in healthy volunteers during LDT, using a short plastic tube.
Thirteen healthy adult volunteers were recruited for the study.
Each subject underwent morning and afternoon LDT via 25 mm plastic intravenous line tube.
In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.