Skip to content

Study · In vitro (cells) · rat · 2018

1 result

Icariside II attenuates cardiac remodeling via AMPKα2/mTORC1 in vivo and in vitro.

Liu XY, Liao HH, Feng H, Zhang N, Yang JJ, Li WJ, Chen S, Deng W, Tang QZ

Journal of pharmacological sciences4 Sept 2018Cited by 22 (Europe PMC)

PMID30241784 (opens in a new tab)DOI10.1016/j.jphs.2018.08.010 (opens in a new tab)PepBankPUB-30241784
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC-ND. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In neonatal rat cardiomyocytes, AICAR and icariside II showed similar AMPKα activation.

    In plain wordsIn cells from newborn rats, AICAR and icariside II showed similar AMPKα activation.

    Peptide
    AICAR (acadesine)
    Outcome
    Direction not reportedAMPKα activation
    Study

    ratn: not reported in source

    Neonatal rat cardiomyocytes
    Comparator
    Icariside II
    Outcome group
    Receptor activity and mechanism · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    ICAII was superior to resveratrol in activating AMPKα and similar to AICAR.
    1 context sentence
    Summary · context
    Additionally, neonatal rat cardiomyocytes (NRCM) were used for in vitro experiments.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

PepBank is a research reference. Talk to a doctor before you use any peptide.