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Study · Measured the body's own peptide · 2018

1 result

Muscle health and performance in monozygotic twins with 30 years of discordant exercise habits.

Bathgate KE, Bagley JR, Jo E, Talmadge RJ, Tobias IS, Brown LE, Coburn JW, Arevalo JA, Segal NL, Galpin AJ

European journal of applied physiology14 Jul 2018Cited by 37 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelCase report or seriesOther

    In one pair of monozygotic twins, the twin with more than 30 years of endurance training had greater muscle IGF1Ec (MGF) mRNA expression than the untrained twin.

    In plain wordsIn one pair of identical twins, the long-time trainer had more of the body's own IGF1Ec (MGF) mRNA in muscle than the untrained twin.

    Outcome
    IncreaseIGF1Ec mRNA expression in skeletal muscle
    Study

    n = 2

    Comparator
    Untrained twin
    Outcome group
    Exercise and physical function · Musculoskeletal

    Source sentences

    Summary
    (5) greater PAX7, IGF1Ec, IGF1Ea, and FN14 mRNA expression than UT.
    2 context sentences
    Summary · context
    One pair of male MZ twins (age = 52 years; Trained Twin, TT; Untrained Twin, UT) underwent analyses of: (1) anthropometric characteristics and blood profiles, (2) markers of cardiovascular and pulmonary health, and (3) skeletal muscle size, strength, and power and molecular markers of muscle health.
    Summary · context
    To enhance the understanding of heritability/adaptability, we explored the skeletal muscle health and physiological performance of monozygotic (MZ) twins with > 30 years of chronic endurance training vs. no specific/consistent exercise.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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