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Study · Not a test of the peptide alone · 2018

2 results

Female Sexual Dysfunction and the Placebo Effect: A Meta-analysis.

Weinberger JM, Houman J, Caron AT, Patel DN, Baskin AS, Ackerman AL, Eilber KS, Anger JT

Obstetrics and gynecology1 Aug 2018Cited by 38 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01HumanNot a test of Oxytocin aloneSystematic reviewEfficacy outcome

    In women with female sexual dysfunction, the Female Sexual Function Index rose by 5.35 in pooled drug treatment arms (including intranasal oxytocin) and by 3.62 in placebo arms.

    In plain wordsIn women with sexual dysfunction, scores rose by 5.35 points with a mix of drugs, intranasal oxytocin among them, and by 3.62 points with placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseFemale Sexual Function Index change in pooled treatment arms
    Study

    n = 2,236

    Outcome group
    Sexual function · Reproductive and sexual health

    Measurements

    FSFI change
    5.35 FSFI points
    pooled treatment arms

    Source sentences

    Summary
    The treatment arm had a corresponding increase of 5.35 (95% CI 4.13-6.57).
    1 context sentence
    Summary · context
    Two thousand two hundred thirty-six women were in the treatment arm of the respective studies and received various pharmacologic interventions including flibanserin, bupropion, onabotulinum toxin A, intravaginal prasterone, intranasal oxytocin, ospemifene, and bremelanotide.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02HumanNot a test of Oxytocin aloneSystematic reviewEfficacy outcome

    In women with female sexual dysfunction, placebo accounted for 67.7% of the treatment effect across pooled drugs, including intranasal oxytocin.

    In plain wordsIn women with sexual dysfunction, placebo explained most of the improvement seen with a mix of drugs, intranasal oxytocin among them.

    Peptide
    Oxytocin
    Outcome
    Not applicableShare of treatment effect explained by placebo
    Study

    n = 2,236

    Outcome group
    Sexual function · Reproductive and sexual health

    Measurements

    Placebo share of treatment effect
    67.7%
    pooled treatment arms

    Source sentences

    Summary
    This meta-analysis of Level I evidence demonstrates that 67.7% of the treatment effect for female sexual dysfunction is accounted for by placebo.
    1 context sentence
    Summary · context
    Two thousand two hundred thirty-six women were in the treatment arm of the respective studies and received various pharmacologic interventions including flibanserin, bupropion, onabotulinum toxin A, intravaginal prasterone, intranasal oxytocin, ospemifene, and bremelanotide.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 3 to 38Current

    28 Oct 2026, 02:04 UTC

    The same notice was added 36 times, first on 9 Oct 2026, 18:17 UTC. The status did not change between them.

    Study results updated

  2. Version 2

    9 Oct 2026, 03:04 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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