In healthy adults, intranasal oxytocin increased task-related activity in a cluster of the left superior temporal gyrus during emotion processing compared with placebo.
In plain wordsIn healthy adults, intranasal oxytocin raised brain activity in the left superior temporal gyrus during emotion tasks compared with placebo.
- Peptide
- Oxytocin
- Outcome
- IncreaseLeft superior temporal gyrus activity during emotion processing tasks (fMRI)
- Study
n: not reported in source
- Comparator
- Placebo
- Outcome group
- Brain and neuronal activity · Nervous system and cognition
- Studied dose
- Dose not stated · intranasalAs given in this study (human).
Source sentences
The meta-analysis identified task-related IN-OXT increases in activity within a cluster of the left superior temporal gyrus during tasks of emotion processing.
2 context sentences(design, population, supporting numbers)
A systematic search of PubMed, PsycINFO, and Scopus databases was conducted for fMRI studies which compared IN-OXT to placebo in humans.
Second, we employed a coordinate-based meta-analysis for task-based neuroimaging literature using activation likelihood estimation (ALE), whereby, coordinates were extracted from clusters with significant differences in IN-OXT versus placebo in healthy adults.