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Study · Measured the body's own peptide · 2018

3 results

Oxytocin- and arginine vasopressin-containing fibers in the cortex of humans, chimpanzees, and rhesus macaques.

Rogers CN, Ross AP, Sahu SP, Siegel ER, Dooyema JM, Cree MA, Stopa EG, Young LJ, Rilling JK, Albers HE, Preuss TM

American journal of primatology24 May 2018Cited by 37 (Europe PMC)

PMID29797339 (opens in a new tab)PMCIDPMC6202198 (opens in a new tab)DOI10.1002/ajp.22875 (opens in a new tab)PepBankPUB-29797339
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In human brain tissue, oxytocin-immunoreactive fibers were present in the straight gyrus of the orbitofrontal cortex and the anterior cingulate gyrus.

    In plain wordsIn human brain tissue, the body's own oxytocin was found in nerve fibers of two cortical regions.

    Peptide
    Oxytocin
    Outcome
    Not applicableOT-immunoreactive fibers in cortex (human)
    Study

    humann: not reported in source

    immunohistochemistry of brain tissue
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    OT-immunoreactive fibers were found in the straight gyrus of the orbitofrontal cortex as well as the anterior cingulate gyrus in human and chimpanzee brains
    1 context sentence
    Summary · context
    Here, we demonstrate the existence of OT- and AVP-containing fibers in cortical regions relevant to social cognition using immunohistochemistry in humans, chimpanzees, and rhesus macaques.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In chimpanzee brain tissue, oxytocin-immunoreactive fibers were present in the straight gyrus of the orbitofrontal cortex and the anterior cingulate gyrus.

    In plain wordsIn chimpanzee brain tissue, the body's own oxytocin was found in nerve fibers of two cortical regions.

    Peptide
    Oxytocin
    Outcome
    Not applicableOT-immunoreactive fibers in cortex (chimpanzee)
    Study

    chimpanzeen: not reported in source

    immunohistochemistry of brain tissue
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    OT-immunoreactive fibers were found in the straight gyrus of the orbitofrontal cortex as well as the anterior cingulate gyrus in human and chimpanzee brains
    1 context sentence
    Summary · context
    Here, we demonstrate the existence of OT- and AVP-containing fibers in cortical regions relevant to social cognition using immunohistochemistry in humans, chimpanzees, and rhesus macaques.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In rhesus macaque cortex, no oxytocin-immunoreactive fibers were found.

    In plain wordsIn rhesus macaque brain tissue, the body's own oxytocin was not found in cortical nerve fibers.

    Peptide
    Oxytocin
    Outcome
    No significant changeOT-immunoreactive fibers in cortex (rhesus macaque)
    Study

    rhesus macaquen: not reported in source

    immunohistochemistry of brain tissue
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    while no OT-immunoreactive fibers were found in macaque cortex.
    1 context sentence
    Summary · context
    Here, we demonstrate the existence of OT- and AVP-containing fibers in cortical regions relevant to social cognition using immunohistochemistry in humans, chimpanzees, and rhesus macaques.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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