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Study · Not a test of the peptide alone · 2018

1 result

Placebo treatment facilitates social trust and approach behavior.

Yan X, Yong X, Huang W, Ma Y

Proceedings of the National Academy of Sciences of the United States of America14 May 2018Cited by 26 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01HumanNot a test of Oxytocin aloneRandomized controlled trialOther

    In humans, the placebo effects on social trust and approach behavior were reported to be as strong as the effect of intranasal oxytocin.

    In plain wordsIn people, a placebo had effects on social trust and approach that could be as strong as those of oxytocin nasal spray.

    Peptide
    Oxytocin
    Outcome
    Not applicablePlacebo effect on social trust and approach compared with intranasal oxytocin
    Study

    n: not reported in source

    Outcome group
    Social behavior and cognition · Mental health and mood

    Source sentences

    Summary
    Finally, we show evidence that the effects of placebo treatment on social trust and approach behavior can be as strong as the effect of intranasal administration of oxytocin, a neuropeptide known for its function in facilitating social cognition and behavior.
    1 context sentence
    Summary · context
    In the present study, we develop and validate a paradigm to induce placebo effects on social trust and approach behavior (social placebo effect), and show robust evidence that placebo treatment promotes trust in others and increases preference for a closer interpersonal distance.

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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