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Study · Randomized controlled trial · n = 33 · 2018

2 results

Effects of intranasal oxytocin on the attentional bias to emotional stimuli in patients with bulimia nervosa.

Kim YR, Eom JS, Leppanen J, Leslie M, Treasure J

Psychoneuroendocrinology3 Mar 2018Cited by 14 (Europe PMC)

PMID29529522 (opens in a new tab)DOI10.1016/j.psyneuen.2018.02.029 (opens in a new tab)PepBankPUB-29529522
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy women, a single intranasal oxytocin dose reduced attentional bias towards angry faces compared with placebo.

    In plain wordsIn healthy women, one dose of oxytocin nasal spray reduced attention to angry faces compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseAttentional bias towards angry faces
    Study

    n = 33

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Intranasal oxytocin reduced the attentional bias towards angry faces in both the BN patients and the healthy women.
    2 context sentences
    Summary · context
    The study design consisted of a double-blind, placebo-controlled within-subject crossover, single dose experiment.
    Summary · context
    Sixty-four women (31 patients with BN and 33 healthy comparisons) completed self-reported measures to evaluate emotional difficulties and were administered a single dose of intranasal oxytocin (40IU) or placebo followed by a visual probe detection task to examine attentional orienting to angry or happy faces.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women with bulimia nervosa, a single intranasal oxytocin dose reduced attentional bias towards angry faces compared with placebo.

    In plain wordsIn women with bulimia nervosa, one dose of oxytocin nasal spray reduced attention to angry faces compared with placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseAttentional bias towards angry faces
    Study

    n = 31

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Intranasal oxytocin reduced the attentional bias towards angry faces in both the BN patients and the healthy women.
    2 context sentences
    Summary · context
    The study design consisted of a double-blind, placebo-controlled within-subject crossover, single dose experiment.
    Summary · context
    Sixty-four women (31 patients with BN and 33 healthy comparisons) completed self-reported measures to evaluate emotional difficulties and were administered a single dose of intranasal oxytocin (40IU) or placebo followed by a visual probe detection task to examine attentional orienting to angry or happy faces.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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