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Study · Randomized controlled trial · n = 120 · 2018

3 results

The effect of oxytocin on group formation and strategic thinking in men.

Aydogan G, Jobst A, Loy F, Dehning S, Zill P, Müller N, Kocher M

Hormones and behavior9 Apr 2018Cited by 5 (Europe PMC)

PMID29526749 (opens in a new tab)DOI10.1016/j.yhbeh.2018.02.003 (opens in a new tab)PepBankPUB-29526749
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In men, intranasal oxytocin had an adverse effect on the choice to form groups in a competitive environment compared with placebo.

    In plain wordsIn men, oxytocin nasal spray made group formation less likely in a competitive setting than placebo did.

    Peptide
    Oxytocin
    Outcome
    DecreaseChoice to form groups in a competitive environment
    Study

    n = 120

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    Here, we show that intranasal administration of Oxytocin (n = 60) compared to placebo (n = 60) in males causes an adverse effect on the choice for forming groups in the presence of a competitive environment.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In men, oxytocin lowered the willingness to work collaboratively in a p-Beauty contest game, most for participants with high strategic sophistication.

    In plain wordsIn men, oxytocin lowered willingness to work together in a game, most in those with high strategic skill.

    Peptide
    Oxytocin
    Outcome
    DecreaseWillingness to work collaboratively in p-Beauty contest game
    Study

    n = 120

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    In particular, Oxytocin negatively affects the willingness to work collaboratively in a p-Beauty contest game, whereas the effect is most pronounced for participants with relatively high strategic sophistication.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In men, the data gave initial evidence that intranasal oxytocin had a positive effect on strategic thinking and performance in the p-Beauty contest game.

    In plain wordsIn men, oxytocin nasal spray showed early signs of better strategic thinking and performance in a game.

    Peptide
    Oxytocin
    Outcome
    IncreaseStrategic thinking and performance in p-Beauty contest game
    Study

    n = 120

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (human).

    Source sentences

    Summary
    our data provide initial evidence that Oxytocin has a positive effect on strategic thinking and performance in the p-Beauty contest game
    1 context sentence
    Summary · context
    Here, we show that intranasal administration of Oxytocin (n = 60) compared to placebo (n = 60) in males causes an adverse effect on the choice for forming groups in the presence of a competitive environment.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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