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Study · Measured the body's own peptide · 2018

1 result

Reduction of respiratory infections in asthma patients supplemented with vitamin D is related to increased serum IL-10 and IFNγ levels and cathelicidin expression.

Ramos-Martínez E, López-Vancell MR, Fernández de Córdova-Aguirre JC, Rojas-Serrano J, Chavarría A, Velasco-Medina A, Velázquez-Sámano G

Cytokine7 May 2018Cited by 52 (Europe PMC)

PMID29402723 (opens in a new tab)DOI10.1016/j.cyto.2018.01.001 (opens in a new tab)PepBankPUB-29402723
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelRandomized controlled trialOther

    In asthma patients given vitamin D, the reduction in respiratory infections was related to the number of patients who expressed LL‑37 in sputum.

    In plain wordsIn people with asthma given vitamin D, fewer infections were linked to having the body's own LL‑37 in sputum.

    Peptide
    LL-37
    Outcome
    Not applicableAssociation of sputum LL-37 expression with fewer respiratory infections
    Study

    n: not reported in source

    Outcome group
    Infection and antimicrobial activity · Respiratory

    Source sentences

    Summary
    Respiratory infections were drastically reduced, and this decrease was related to the number of patients who had high serum levels of IL-10 and IFNγ and expressed LL-37 in their sputum.
    3 context sentences
    Summary · context
    This study was conducted in 86 patients between 18 and 50 years of age who were randomly divided into two groups.
    Summary · context
    One group also received calcitriol (1,25-(OH)2D3), and the other group received a placebo.
    Summary · context
    At baseline and 6 months, skin prick tests were conducted, pharyngeal bacterial cultures were performed, and cathelicidin LL-37 was measured in sputum.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:57 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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