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Study · Not a test of the peptide alone · 2018

1 result

Listeria monocytogenes endocarditis: case report, review of the literature, and laboratory evaluation of potential novel antibiotic synergies.

Kumaraswamy M, Do C, Sakoulas G, Nonejuie P, Tseng GW, King H, Fierer J, Pogliano J, Nizet V

International journal of antimicrobial agents11 Jan 2018Cited by 22 (Europe PMC)

PMID29337066 (opens in a new tab)PMCIDPMC5860678 (opens in a new tab)DOI10.1016/j.ijantimicag.2017.12.032 (opens in a new tab)PepBankPUB-29337066
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking LL-37.

  1. 01LabNot a test of LL-37 aloneIn vitro (cells)Activity measurement

    In lab tests, antibiotic pretreatment of a Listeria monocytogenes endocarditis isolate did not potentiate killing by the human cathelicidin LL‑37.

    In plain wordsIn lab tests, giving antibiotics first did not make Listeria easier for LL‑37 to kill.

    Peptide
    LL-37
    Outcome
    No significant changePotentiation of LL-37 activity by antibiotic pretreatment
    Study

    Listeria monocytogenesn: not reported in source

    L. monocytogenes endocarditis isolate
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    However, these effects did not reflect potentiation of antibiotic activity to human cathelicidin peptide LL-37, which is abundant in neutrophils and highly active against LM.
    1 context sentence
    Summary · context
    Here we report a case of LM endocarditis, review the world literature, and evaluate alternative treatment strategies for listeriosis utilizing in vitro and ex vivo studies.

    In this study, LL-37 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking LL-37.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:57 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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