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Study · In vitro (cells) · 2017

3 results

[Effect of combined application of ozone therapy and gravitational therapy on the remote results of complex treatment of geriatric patients].

Fridman NV, Linkova NS, Polyakova VO, Drobintseva AO, Тrofimova SV, Kvetnoy IM, Khavinson VK

Advances in gerontology = Uspekhi gerontologii1 Jan 2017

PMID29322736 (opens in a new tab)PepBankPUB-29322736
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In old human skin fibroblast cultures, KE dipeptide increased collagen type I expression area by 83%.

    In plain wordsIn cells, KE dipeptide increased collagen expression in old human skin fibroblasts.

    Peptide
    Vilon (KE)
    Outcome
    IncreaseCollagen type I expression area
    Study

    humann: not reported in source

    Cultured human skin fibroblasts
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Measurements

    Collagen type I expression area increase
    83%
    old fibroblasts

    Source sentences

    Summary
    KE dipeptide increases collagen type I expression area in «old» skin fibroblasts cultures by 83%.
    1 context sentence
    Summary · context
    This research is aimed at investigation of KE (Lys-Glu, Vilon) dipeptide influence on the expression of markers of aging in human skin fibroblasts in vitro. Collagen type I and sirtuin-6 expression in «young» and «old» skin cell fibroblasts cultures was studied using immunofluorescence confocal microscopy method.
  2. 02LabIn vitro (cells)Mechanism

    In young human skin fibroblast cultures, KE dipeptide increased sirtuin-6 expression area 1.6-fold.

    In plain wordsIn cells, KE dipeptide increased sirtuin-6 expression in young human skin fibroblasts.

    Peptide
    Vilon (KE)
    Outcome
    IncreaseSirtuin-6 expression area in young fibroblasts
    Study

    humann: not reported in source

    Cultured human skin fibroblasts
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Measurements

    Sirtuin-6 expression area
    1.6 times
    young fibroblasts

    Source sentences

    Summary
    KE dipeptide increases expression area of sirtuin-6 in «young» and «old» skin fibroblasts cultures by 1,6 and 2,6 times correspondingly.
    1 context sentence
    Summary · context
    This research is aimed at investigation of KE (Lys-Glu, Vilon) dipeptide influence on the expression of markers of aging in human skin fibroblasts in vitro. Collagen type I and sirtuin-6 expression in «young» and «old» skin cell fibroblasts cultures was studied using immunofluorescence confocal microscopy method.
  3. 03LabIn vitro (cells)Mechanism

    In old human skin fibroblast cultures, KE dipeptide increased sirtuin-6 expression area 2.6-fold.

    In plain wordsIn cells, KE dipeptide increased sirtuin-6 expression in old human skin fibroblasts.

    Peptide
    Vilon (KE)
    Outcome
    IncreaseSirtuin-6 expression area in old fibroblasts
    Study

    humann: not reported in source

    Cultured human skin fibroblasts
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated

    Measurements

    Sirtuin-6 expression area
    2.6 times
    old fibroblasts

    Source sentences

    Summary
    KE dipeptide increases expression area of sirtuin-6 in «young» and «old» skin fibroblasts cultures by 1,6 and 2,6 times correspondingly.
    1 context sentence
    Summary · context
    This research is aimed at investigation of KE (Lys-Glu, Vilon) dipeptide influence on the expression of markers of aging in human skin fibroblasts in vitro. Collagen type I and sirtuin-6 expression in «young» and «old» skin cell fibroblasts cultures was studied using immunofluorescence confocal microscopy method.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 17:05 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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