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Study · Ex vivo tissue · rat · 2018

3 results

Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices.

Kolbaev SN, Aleksandrova OP, Sharonova IN, Skrebitsky VG

Bulletin of experimental biology and medicine8 Jan 2018Cited by 2 (Europe PMC)

PMID29313229 (opens in a new tab)DOI10.1007/s10517-018-3983-3 (opens in a new tab)PepBankPUB-29313229
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In cultured rat hippocampal slices, Noopept increased spontaneous calcium transient frequency in CA1 radial-layer neurons.

    In plain wordsIn lab tests on rat hippocampal slices, Noopept increased calcium transient frequency in radial-layer neurons.

    Peptide
    Noopept (omberacetam)
    Outcome
    IncreaseSpontaneous calcium transient frequency
    Study

    ratn: not reported in source

    Cultured hippocampal slices
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices.
  2. 02LabEx vivo tissueActivity measurement

    In cultured rat hippocampal slices, Noopept did not significantly affect intracellular calcium concentration in CA1 pyramidal neurons.

    In plain wordsIn lab tests on rat hippocampal slices, Noopept did not significantly change calcium concentration in pyramidal neurons.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeIntracellular calcium concentration
    Study

    ratn: not reported in source

    Cultured hippocampal slices
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In contrast, the drug exerted no significant effect on intracellular calcium concentration and its dynamics in neurons of hippocampal CA1 pyramidal layer.
  3. 03LabEx vivo tissueActivity measurement

    In cultured rat hippocampal slices, Noopept did not significantly affect intracellular calcium dynamics in CA1 pyramidal neurons.

    In plain wordsIn lab tests on rat hippocampal slices, Noopept did not significantly change calcium dynamics in pyramidal neurons.

    Peptide
    Noopept (omberacetam)
    Outcome
    No significant changeIntracellular calcium dynamics
    Study

    ratn: not reported in source

    Cultured hippocampal slices
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In contrast, the drug exerted no significant effect on intracellular calcium concentration and its dynamics in neurons of hippocampal CA1 pyramidal layer.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

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