[Disorders in structural-functional properties of erythrocytes in experimental acute destructive pancreatitis of alcohol etiology and their correction].

Konoplja AI, Litvinova ES, Sunyaykina OA, Bushmina ON, Harchenko AV, Konoplja AA

Biomeditsinskaia khimiia1 Nov 2017Cited by 1 (Europe PMC)

PMID29251614DOI10.18097/pbmc20176306527PepBankPUB-29251614

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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Gepon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Gepon.

01AnimalNot a test of Gepon aloneAnimal study (in vivo)Efficacy outcome
In rats with alcohol-related acute destructive pancreatitis, Hepon with Hypoxenum and Phosphogliv normalized 22.5% of altered parameters.
In plain wordsIn rats with alcohol-related pancreatitis, the Hepon combination normalized 22.5% of altered red blood cell parameters.
Peptide
Gepon
Outcome
Not applicableNormalization of altered RBC parameters
Study
ratn: not reported in source
Male Wistar rats with acute destructive pancreatitis under chronic alcoholization
Outcome group
Blood counts and hematopoiesis · Whole body
Measurements
Normalized parameters
22.5%
Hepon, Hypoxenum and Phosphogliv
Source sentences
Summary
Administration of a combination of Hepon, Hypoxenum, and Phosphogliv normalized 22.5% of parameters altered change during development of acute destructive pancreatitis under conditions of chronic alcoholization of parameters, corrected towards normal values 42.5% of parameters (35% of parameters remained unchanged).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of various combinations of pharmacological agents on parameters characterizing red blood cell (RBC) membrane proteins and lipids have been investigated in RBC isolated from Wistar male rats with acute destructive pancreatitis induced under conditions of forced alcoholization for 60 days.
In this study, Gepon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gepon.
Report a problemFND-2925161401
02AnimalNot a test of Gepon aloneAnimal study (in vivo)Efficacy outcome
In rats with alcohol-related acute destructive pancreatitis, Hepon with Hypoxenum and Phosphogliv corrected 42.5% of parameters toward normal values.
In plain wordsIn rats with alcohol-related pancreatitis, the Hepon combination corrected 42.5% of red blood cell parameters toward normal values.
Peptide
Gepon
Outcome
Not applicableCorrection of altered RBC parameters toward normal
Study
ratn: not reported in source
Male Wistar rats with acute destructive pancreatitis under chronic alcoholization
Outcome group
Blood counts and hematopoiesis · Whole body
Measurements
Parameters corrected toward normal
42.5%
Hepon, Hypoxenum and Phosphogliv
Source sentences
Summary
Administration of a combination of Hepon, Hypoxenum, and Phosphogliv normalized 22.5% of parameters altered change during development of acute destructive pancreatitis under conditions of chronic alcoholization of parameters, corrected towards normal values 42.5% of parameters (35% of parameters remained unchanged).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of various combinations of pharmacological agents on parameters characterizing red blood cell (RBC) membrane proteins and lipids have been investigated in RBC isolated from Wistar male rats with acute destructive pancreatitis induced under conditions of forced alcoholization for 60 days.
In this study, Gepon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gepon.
Report a problemFND-2925161402
03AnimalNot a test of Gepon aloneAnimal study (in vivo)Efficacy outcome
In rats with alcohol-related acute destructive pancreatitis, 35% of parameters remained unchanged after Hepon with Hypoxenum and Phosphogliv.
In plain wordsIn rats with alcohol-related pancreatitis, 35% of red blood cell parameters remained unchanged after the Hepon combination.
Peptide
Gepon
Outcome
No significant changeUnchanged altered RBC parameters
Study
ratn: not reported in source
Male Wistar rats with acute destructive pancreatitis under chronic alcoholization
Outcome group
Blood counts and hematopoiesis · Whole body
Measurements
Unchanged parameters
35%
Hepon, Hypoxenum and Phosphogliv
Source sentences
Summary
Administration of a combination of Hepon, Hypoxenum, and Phosphogliv normalized 22.5% of parameters altered change during development of acute destructive pancreatitis under conditions of chronic alcoholization of parameters, corrected towards normal values 42.5% of parameters (35% of parameters remained unchanged).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of various combinations of pharmacological agents on parameters characterizing red blood cell (RBC) membrane proteins and lipids have been investigated in RBC isolated from Wistar male rats with acute destructive pancreatitis induced under conditions of forced alcoholization for 60 days.
In this study, Gepon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gepon.
Report a problemFND-2925161403

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
27 Oct 2026, 18:20 UTC
Study results updated
Version 1
27 Oct 2026, 16:32 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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Journal Article

MeSH terms

Keywords

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