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Study · Ex vivo tissue · 2017

2 results

Anticoagulant Effects of Arginine-Containing Peptides of the Glyproline Family (His-Phe-Arg-Trp-Pro-Gly-Pro and Thr-Lys-Pro-Arg-Pro-Gly-Pro) Revealed by Thromboelastography.

Rogozinskaya EY, Lyapina MG

Bulletin of experimental biology and medicine27 Nov 2017Cited by 1 (Europe PMC)

PMID29181670 (opens in a new tab)DOI10.1007/s10517-017-3950-4 (opens in a new tab)PepBankPUB-29181670
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In thromboelastography, Selank changed the parameters R, K, MA, S, TMA and J toward hypocoagulation compared with control.

    In plain wordsIn lab tests, Selank made blood clotting measures shift toward weaker clotting compared with control.

    Peptide
    Selank
    Outcome
    DecreaseThromboelastography parameters R, K, MA, S, TMA and J
    Study

    n: not reported in source

    Thromboelastography
    Comparator
    Control
    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro. The parameters R, K, MA, S, TMA, and J changed to hypocoagulation direction in comparison to the control.
  2. 02LabEx vivo tissueActivity measurement

    In thromboelastography, Selank had the maximal anticoagulation potency among the three glyproline oligopeptides tested.

    In plain wordsIn lab tests, Selank slowed clotting more than the two other glyproline peptides tested.

    Peptide
    Selank
    Outcome
    DecreaseAnticoagulation potency versus other glyproline peptides
    Study

    n: not reported in source

    Thromboelastography
    Comparator
    His-Phe-Arg-Trp-Pro-Gly-Pro; Pro-Gly-Pro
    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At this, Selank demonstrated the maximal anticoagulation potency.
    1 context sentence
    Summary · context
    Thromboelastography revealed anticoagulant effects of 3 glyproline oligopeptides (in various concentrations): His-Phe-Arg-Trp-Pro-Gly-Pro, Thr-Lys-Pro-Arg-Pro-Gly-Pro (Selank), and Pro-Gly-Pro.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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