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Study · Animal study (in vivo) · rat · 2017

4 results

Effect of cerebrolysin on the cerebellum of diabetic rats: An imunohistochemical study.

Sherif RN

Tissue & cell25 Oct 2017Cited by 11 (Europe PMC)

PMID29107328 (opens in a new tab)DOI10.1016/j.tice.2017.10.006 (opens in a new tab)PepBankPUB-29107328
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Cerebrolysin reduced changes in cerebellar oxidative stress markers compared with untreated diabetic rats.

    In plain wordsIn diabetic rats, Cerebrolysin reduced changes in cerebellar oxidative stress markers compared with untreated diabetic rats.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseOxidative stress marker changes
    Study

    ratn: not reported in source

    Diabetic Sprague Dawley male rats
    Comparator
    Diabetes without Cbl
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although Cbl treatment succeeded in minimizing the changes in the oxidative stress markers, it had no effect on pathological changes of the diabetic cerebellum.
    1 context sentence
    Summary · context
    Sprague Dawley male rats were divided randomly into four groups: control, cerebrolysin (Cbl), diabetes and diabetes treated with Cbl groups.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In diabetic rats, Cerebrolysin did not change cerebellar pathological changes compared with untreated diabetic rats.

    In plain wordsIn diabetic rats, Cerebrolysin did not change cerebellar pathological changes compared with untreated diabetic rats.

    Peptide
    Cerebrolysin
    Outcome
    No significant changeCerebellar pathological changes
    Study

    ratn: not reported in source

    Diabetic Sprague Dawley male rats
    Comparator
    Diabetes without Cbl
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Although Cbl treatment succeeded in minimizing the changes in the oxidative stress markers, it had no effect on pathological changes of the diabetic cerebellum.
    1 context sentence
    Summary · context
    Sprague Dawley male rats were divided randomly into four groups: control, cerebrolysin (Cbl), diabetes and diabetes treated with Cbl groups.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In diabetic rats, Cerebrolysin reduced cerebellar GFAP-positive area fraction compared with untreated diabetic rats.

    In plain wordsIn diabetic rats, Cerebrolysin reduced cerebellar GFAP-positive area fraction compared with untreated diabetic rats.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseGFAP positive area fraction
    Study

    ratn: not reported in source

    Diabetic Sprague Dawley male rats
    Comparator
    Diabetes without Cbl
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cerebrolysin treatment of diabetic rats decreased the area fraction of GFAP positive immunoreactivity and had no effect on synaptophysin expression.
    1 context sentence
    Summary · context
    Sprague Dawley male rats were divided randomly into four groups: control, cerebrolysin (Cbl), diabetes and diabetes treated with Cbl groups.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In diabetic rats, Cerebrolysin did not change cerebellar synaptophysin expression compared with untreated diabetic rats.

    In plain wordsIn diabetic rats, Cerebrolysin did not change cerebellar synaptophysin expression compared with untreated diabetic rats.

    Peptide
    Cerebrolysin
    Outcome
    No significant changeSynaptophysin expression
    Study

    ratn: not reported in source

    Diabetic Sprague Dawley male rats
    Comparator
    Diabetes without Cbl
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cerebrolysin treatment of diabetic rats decreased the area fraction of GFAP positive immunoreactivity and had no effect on synaptophysin expression.
    1 context sentence
    Summary · context
    Sprague Dawley male rats were divided randomly into four groups: control, cerebrolysin (Cbl), diabetes and diabetes treated with Cbl groups.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

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