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Study · Measured the body's own peptide · 2018

2 results

Oxytocin plasma levels predict the outcome of psychotherapy: A pilot study in chronic depression.

Jobst A, Sabaß L, Hall D, Brücklmeier B, Buchheim A, Hall J, Sarubin N, Zill P, Falkai P, Brakemeier EL, Padberg F

Journal of affective disorders24 Oct 2017Cited by 23 (Europe PMC)

PMID29100154 (opens in a new tab)DOI10.1016/j.jad.2017.10.037 (opens in a new tab)PepBankPUB-29100154
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patients with chronic depression, lower baseline oxytocin plasma levels correlated with smaller changes in BDI-II scores after psychotherapy.

    In plain wordsIn people with chronic depression, lower natural oxytocin levels before therapy were linked to a smaller improvement in depression scores.

    Peptide
    Oxytocin
    Outcome
    Not applicableBaseline oxytocin plasma level and change in BDI-II score
    Study

    n = 16

    Outcome group
    Overall treatment effect · Mental health and mood

    Source sentences

    Summary
    Lower oxytocin plasma levels at baseline correlated with smaller changes in BDI-II scores
    2 context sentences
    Summary · context
    Sixteen patients with chronic depression participated in a 10-week CBASP inpatient program.
    Summary · context
    Oxytocin plasma levels were measured before and after participants played a virtual ball-tossing game (Cyberball) that mimics social exclusion.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patients with chronic depression, baseline oxytocin plasma levels did not correlate with the change in HAMD-24 scores after psychotherapy.

    In plain wordsIn people with chronic depression, natural oxytocin levels before therapy were not linked to the change in HAMD-24 depression scores.

    Peptide
    Oxytocin
    Outcome
    No significant changeBaseline oxytocin plasma level and change in HAMD-24 score
    Study

    n = 16

    Outcome group
    Overall treatment effect · Mental health and mood

    Source sentences

    Summary
    Lower oxytocin plasma levels at baseline correlated with smaller changes in BDI-II scores, but not with the change in HAMD-24 scores.
    2 context sentences
    Summary · context
    Sixteen patients with chronic depression participated in a 10-week CBASP inpatient program.
    Summary · context
    Oxytocin plasma levels were measured before and after participants played a virtual ball-tossing game (Cyberball) that mimics social exclusion.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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