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Study · Not a test of the peptide alone · 2018

2 results

Central ghrelin receptor stimulation modulates sex motivation in male rats in a site dependent manner.

Hyland L, Rosenbaum S, Edwards A, Palacios D, Graham MD, Pfaus JG, Woodside B, Abizaid A

Hormones and behavior8 Nov 2017Cited by 15 (Europe PMC)

PMID29080670 (opens in a new tab)DOI10.1016/j.yhbeh.2017.10.012 (opens in a new tab)PepBankPUB-29080670
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In food-deprived male rats, intra-VTA D-Lys-GHRP6 further decreased sex anticipation.

    In plain wordsIn food-deprived male rats, D-Lys-GHRP6 infusion into the VTA further reduced anticipation of sex.

    Peptide
    GHRP-6
    Outcome
    DecreaseSex anticipation after VTA antagonist infusion
    Study

    ratn: not reported in source

    male Long Evans rats
    Outcome group
    Sexual function · Reproductive and sexual health

    Source sentences

    Summary
    Furthermore, although ghrelin does not further stimulate sex anticipation in rats when infused into the VTA, intra-VTA infusions of D-Lys-GHRP6 into the VTA further decreases in sex anticipation in food deprived rats.
    1 context sentence
    Summary · context
    We also examined the effects of ghrelin or the ghrelin antagonist D-Lys-GHRP6 delivered into the VTA or the MPOA on appetitive and consummatory sex behaviors in male Long Evans rats.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02AnimalNot a test of GHRP-6 aloneAnimal study (in vivo)Efficacy outcome

    In male rats, sex anticipation was higher after mPOA D-Lys-GHRP6 infusion than after mPOA ghrelin infusion.

    In plain wordsIn male rats, D-Lys-GHRP6 in the mPOA produced greater anticipation of sex than ghrelin in the mPOA.

    Peptide
    GHRP-6
    Outcome
    IncreaseSex anticipation after mPOA infusion versus ghrelin
    Study

    ratn: not reported in source

    male Long Evans rats
    Comparator
    Ghrelin infusion into mPOA
    Outcome group
    Sexual function · Reproductive and sexual health

    Source sentences

    Summary
    In contrast, ghrelin delivery into the mPOA decreased sex anticipation compared to saline or D-Lys-GHRP6 infused rats.
    1 context sentence
    Summary · context
    We also examined the effects of ghrelin or the ghrelin antagonist D-Lys-GHRP6 delivered into the VTA or the MPOA on appetitive and consummatory sex behaviors in male Long Evans rats.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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