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Study · Randomized controlled trial · n = 24 · 2017

2 results

Electrophysiological correlates of oxytocin-induced enhancement of social performance monitoring.

de Bruijn ERA, Ruissen MI, Radke S

Social cognitive and affective neuroscience1 Oct 2017Cited by 19 (Europe PMC)

PMID28985434 (opens in a new tab)PMCIDPMC5647804 (opens in a new tab)DOI10.1093/scan/nsx094 (opens in a new tab)PepBankPUB-28985434
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Summary

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Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialMechanism

    In healthy men, after oxytocin the error-related negativity amplitude was increased for social compared with individual mistakes, and not so after placebo.

    In plain wordsIn healthy men, oxytocin made a brain response to errors larger for social mistakes than for individual ones, unlike placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseError-related negativity amplitude for social versus individual mistakes
    Study

    n = 24

    Comparator
    Placebo
    Outcome group
    Brain and neuronal activity · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Following oxytocin administration, error-related negativity amplitudes were increased for social compared with individual mistakes. This increase was not found in the placebo condition.
    1 context sentence
    Summary · context
    Healthy male volunteers (N = 24) participated in a placebo-controlled crossover design.
  2. 02HumanRandomized controlled trialMechanism

    In healthy men, oxytocin had no effects on performance monitoring in the individual context.

    In plain wordsIn healthy men, oxytocin had no effect on brain responses to errors made when working alone.

    Peptide
    Oxytocin
    Outcome
    No significant changeError-related negativity in the individual context
    Study

    n = 24

    Comparator
    Placebo
    Outcome group
    Brain and neuronal activity · Nervous system and cognition
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    No effects of oxytocin were present in the individual context.
    1 context sentence
    Summary · context
    Healthy male volunteers (N = 24) participated in a placebo-controlled crossover design.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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