In female rats exposed to permanent artificial lighting and 1,2-dimethylhydrazine, melatonin and epitalon corrected a number of impairments of the hypothalamic-pituitary-gonadal axis.
In plain wordsIn female rats exposed to constant light and a toxic chemical, melatonin and epitalon corrected some impairments of the reproductive hormone axis.
- Peptide
- Epitalon
- Outcome
- MixedHypothalamic-pituitary-gonadal axis impairments
- Study
ratn: not reported in source
Female rats under permanent artificial lighting and 1,2-dimethylhydrazine- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Source sentences
Administration of the pineal gland peptide melatonin and peptide preparation epitalon was shown to be able to correct a number of impairments of the hypothalamic-pituitary-gonadal axis that can be observed, when the experimental animals were exposed to permanent artificial lighting and a neurotoxic…
1 context sentence(design, population, supporting numbers)
Potential neuroprotective effects of the pineal gland hormone melatonin and peptide preparation epitalon on estrous cycles and the central regulation of reproduction in female rats exposed to unfavourable environmental factors have been studied.
In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.