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Study · Measured the body's own peptide · 2017

5 results

Serum level of cathelicidin LL-37 in patients with active tuberculosis and other infectious diseases.

Majewski K, Agier J, Kozłowska E, Brzezińska-Błaszczyk E

Journal of biological regulators and homeostatic agents1 Jul 2017Cited by 11 (Europe PMC)

PMID28956425 (opens in a new tab)PepBankPUB-28956425
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In patients with pulmonary tuberculosis, serum LL‑37 was not significantly correlated with CRP concentration.

    In plain wordsIn people with tuberculosis, natural LL‑37 in blood was not linked to CRP, a marker of inflammation.

    Peptide
    LL-37
    Outcome
    No significant changeCorrelation of serum LL-37 with CRP in TB
    Study

    n = 50

    Outcome group
    Inflammation markers · Infection

    Measurements

    Correlation coefficient (r)
    −0.2042 r
    serum LL-37 vs CRP in TB patients

    Source sentences

    Summary
    In patients with TB, no statistically significant correlations between serum LL-37 and CRP concentrations (r = -0.2042; p = 0.189)
    2 context sentences
    Summary · context
    Fifty patients with pulmonary TB, 31 patients with pneumonia caused by gram-positive bacteria, 68 individuals with pneumonia caused by Gram-negative bacteria, and 61 randomly selected healthy subjects were enrolled in the study.
    Summary · context
    Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In patients with pulmonary tuberculosis, serum LL‑37 was not significantly correlated with WBC count.

    In plain wordsIn people with tuberculosis, natural LL‑37 in blood was not linked to white blood cell count.

    Peptide
    LL-37
    Outcome
    No significant changeCorrelation of serum LL-37 with WBC count in TB
    Study

    n = 50

    Outcome group
    Inflammation markers · Infection

    Measurements

    Correlation coefficient (r)
    −0.1277 r
    serum LL-37 vs WBC count in TB patients

    Source sentences

    Summary
    and between serum LL-37 concentration and WBC count (r = -0.1277; p = 0.414) were observed.
    2 context sentences
    Summary · context
    Fifty patients with pulmonary TB, 31 patients with pneumonia caused by gram-positive bacteria, 68 individuals with pneumonia caused by Gram-negative bacteria, and 61 randomly selected healthy subjects were enrolled in the study.
    Summary · context
    Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  3. 03HumanEndogenous levelObservational studyOther

    Mean serum LL‑37 was significantly higher in adults with pulmonary tuberculosis than in patients with Gram-positive pneumonia.

    In plain wordsNatural LL‑37 in blood was higher in adults with tuberculosis than in people with Gram-positive pneumonia.

    Peptide
    LL-37
    Outcome
    IncreaseSerum LL-37 in TB versus Gram-positive pneumonia
    Study

    n: not reported in source

    Comparator
    Patients with Gram-positive bacterial pneumonia
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    We established that the mean level of LL-37 was statistically significantly higher in TB patients than that in patients with Gram-positive bacteria-induced pneumonia (p < 0.001), in patients with Gram-negative bacteria-induced pneumonia (p < 0.001), and in healthy controls (p < 0.001).
    2 context sentences
    Summary · context
    Fifty patients with pulmonary TB, 31 patients with pneumonia caused by gram-positive bacteria, 68 individuals with pneumonia caused by Gram-negative bacteria, and 61 randomly selected healthy subjects were enrolled in the study.
    Summary · context
    Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  4. 04HumanEndogenous levelObservational studyOther

    Mean serum LL‑37 was significantly higher in adults with pulmonary tuberculosis than in patients with Gram-negative pneumonia.

    In plain wordsNatural LL‑37 in blood was higher in adults with tuberculosis than in people with Gram-negative pneumonia.

    Peptide
    LL-37
    Outcome
    IncreaseSerum LL-37 in TB versus Gram-negative pneumonia
    Study

    n: not reported in source

    Comparator
    Patients with Gram-negative bacterial pneumonia
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    We established that the mean level of LL-37 was statistically significantly higher in TB patients than that in patients with Gram-positive bacteria-induced pneumonia (p < 0.001), in patients with Gram-negative bacteria-induced pneumonia (p < 0.001), and in healthy controls (p < 0.001).
    2 context sentences
    Summary · context
    Fifty patients with pulmonary TB, 31 patients with pneumonia caused by gram-positive bacteria, 68 individuals with pneumonia caused by Gram-negative bacteria, and 61 randomly selected healthy subjects were enrolled in the study.
    Summary · context
    Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  5. 05HumanEndogenous levelObservational studyOther

    Mean serum LL‑37 was significantly higher in adults with pulmonary tuberculosis than in healthy controls.

    In plain wordsNatural LL‑37 in blood was higher in adults with tuberculosis than in healthy people.

    Peptide
    LL-37
    Outcome
    IncreaseSerum LL-37 in TB versus healthy controls
    Study

    n: not reported in source

    Comparator
    Healthy controls
    Outcome group
    Infection and antimicrobial activity · Infection

    Source sentences

    Summary
    We established that the mean level of LL-37 was statistically significantly higher in TB patients than that in patients with Gram-positive bacteria-induced pneumonia (p < 0.001), in patients with Gram-negative bacteria-induced pneumonia (p < 0.001), and in healthy controls (p < 0.001).
    2 context sentences
    Summary · context
    Fifty patients with pulmonary TB, 31 patients with pneumonia caused by gram-positive bacteria, 68 individuals with pneumonia caused by Gram-negative bacteria, and 61 randomly selected healthy subjects were enrolled in the study.
    Summary · context
    Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:57 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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