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Study · Animal study (in vivo) · rat · 2017

2 results

Changes in Sympathetic Innervation of the Heart in Rats with Experimental Myocardial Infarction. Effect of Semax.

Gavrilova SA, Markov MA, Berdalin AB, Kurenkova AD, Koshelev VB

Bulletin of experimental biology and medicine25 Sept 2017Cited by 2 (Europe PMC)

PMID28948544 (opens in a new tab)DOI10.1007/s10517-017-3862-3 (opens in a new tab)PepBankPUB-28948544
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats 28 days after myocardial ischemia/reperfusion injury, Semax diminished the growth of sympathetic innervation of the ventricular septum.

    In plain wordsIn rats after a heart attack, Semax reduced the growth of sympathetic nerves in the heart wall.

    Peptide
    Semax
    Outcome
    DecreaseSympathetic innervation of ventricular septum
    Study

    ratn: not reported in source

    experimental myocardial infarction (ischemia/reperfusion)
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Semax diminished the growth of sympathetic innervation of ventricular septum
    1 context sentence
    Summary · context
    The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats 28 days after myocardial ischemia/reperfusion injury, Semax had no effect on the density of β1 and β2 adrenoceptors.

    In plain wordsIn rats after a heart attack, Semax did not change the density of β1 and β2 adrenoceptors.

    Peptide
    Semax
    Outcome
    No significant changeβ1 and β2 adrenoceptor density
    Study

    ratn: not reported in source

    experimental myocardial infarction (ischemia/reperfusion)
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    although it produced no effect on the density of β1 and β2 adrenoceptors.
    1 context sentence
    Summary · context
    The effect of peptide Semax on remodeling of cardiac sympathetic innervation was examined in rats with experimental myocardial infarction.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 19:08 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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