In elderly patients with amnestic mild cognitive impairment, antibodies against P75NTR significantly decreased after 5.5 month of Cerebrolysin treatment.
In plain wordsIn elderly patients with mild cognitive impairment, P75NTR antibodies decreased after Cerebrolysin treatment compared with pretreatment levels.
- Peptide
- Cerebrolysin
- Outcome
- DecreaseAntibodies against P75NTR
- Study
n = 19
- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- 30 ml · intravenousAs given in this study (human).
Source sentences
The study showed that аMCI patients had an increased level of antibodies against P75NTR that was significantly decreased after 5.5 month of cerebrolysin treatment.
2 context sentences(design, population, supporting numbers)
The study involved a group of 19 elderly patients who met the diagnostic criteria of aMCI.
All patients received a course of neurotrophic therapy consisting of 20 intravenous infusions of cerebrolysin (30 ml of cerebrolysin in 100 ml of isotonic sodium chloride solution).