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Study · Not a test of the peptide alone · 2017

4 results

Laparoscopic Sleeve Gastrectomy Resolves Low GHRP-2-Stimulated Growth Hormone Levels in Obese Patients.

Ohara E, Tokuyama H, Kitamoto T, Kitahara A, Hayashi A, Hayashi H, Takemoto M, Yokote K

Obesity surgery1 Aug 2017Cited by 3 (Europe PMC)

PMID28623445 (opens in a new tab)DOI10.1007/s11695-017-2769-4 (opens in a new tab)PepBankPUB-28623445
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-2.

  1. 01HumanNot a test of GHRP-2 aloneObservational studyOther

    In 28 obese individuals, peak GH after the GHRP‑2 load test correlated negatively with BMI.

    In plain wordsIn people with obesity, a higher BMI went with a lower growth hormone peak after a GHRP‑2 test.

    Peptide
    GHRP-2
    Outcome
    DecreaseGH peak correlation with BMI
    Study

    n = 28

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    Correlation
    −0.59 r
    GH peak vs BMI

    Source sentences

    Summary
    In the univariate analysis, GH secretion peaks correlated negatively with BMI (r = -0.59, p = 0.001), visceral adipose tissue (r = -0.47, p = 0.005), and subcutaneous adipose tissue (r = -0.40, p = 0.04).
    1 context sentence
    Summary · context
    Because growth hormone (GH) secretion is reportedly decreased in obese patients, we examined not only the factors associated with the decreased GH secretion but also GH response to the GH-releasing peptide (GHRP)-2-load test before and after laparoscopic gastrectomy (LSG). The study comprised 28 ind…

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  2. 02HumanNot a test of GHRP-2 aloneObservational studyOther

    In 28 obese individuals, peak GH after the GHRP‑2 load test correlated negatively with visceral adipose tissue.

    In plain wordsMore belly fat went with a lower growth hormone peak after a GHRP‑2 test.

    Peptide
    GHRP-2
    Outcome
    DecreaseGH peak correlation with visceral adipose tissue
    Study

    n = 28

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    Correlation
    −0.47 r
    GH peak vs visceral adipose tissue

    Source sentences

    Summary
    In the univariate analysis, GH secretion peaks correlated negatively with BMI (r = -0.59, p = 0.001), visceral adipose tissue (r = -0.47, p = 0.005), and subcutaneous adipose tissue (r = -0.40, p = 0.04).
    1 context sentence
    Summary · context
    Because growth hormone (GH) secretion is reportedly decreased in obese patients, we examined not only the factors associated with the decreased GH secretion but also GH response to the GH-releasing peptide (GHRP)-2-load test before and after laparoscopic gastrectomy (LSG). The study comprised 28 ind…

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  3. 03HumanNot a test of GHRP-2 aloneObservational studyOther

    In 28 obese individuals, peak GH after the GHRP‑2 load test correlated negatively with subcutaneous adipose tissue.

    In plain wordsMore fat under the skin went with a lower growth hormone peak after a GHRP‑2 test.

    Peptide
    GHRP-2
    Outcome
    DecreaseGH peak correlation with subcutaneous adipose tissue
    Study

    n = 28

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    Correlation
    −0.4 r
    GH peak vs subcutaneous adipose tissue

    Source sentences

    Summary
    In the univariate analysis, GH secretion peaks correlated negatively with BMI (r = -0.59, p = 0.001), visceral adipose tissue (r = -0.47, p = 0.005), and subcutaneous adipose tissue (r = -0.40, p = 0.04).
    1 context sentence
    Summary · context
    Because growth hormone (GH) secretion is reportedly decreased in obese patients, we examined not only the factors associated with the decreased GH secretion but also GH response to the GH-releasing peptide (GHRP)-2-load test before and after laparoscopic gastrectomy (LSG). The study comprised 28 ind…

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

  4. 04HumanNot a test of GHRP-2 aloneObservational studyOther

    In two obese patients, the GH response to the GHRP‑2 load test improved markedly after weight loss 12 months after laparoscopic sleeve gastrectomy.

    In plain wordsIn two patients, the growth hormone response to GHRP‑2 improved after weight loss from surgery.

    Peptide
    GHRP-2
    Outcome
    IncreaseGH response to GHRP-2 load test after sleeve gastrectomy
    Study

    n = 2

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    In the two obese patients, the response to the GHRP-2-load test markedly improved by weight loss 12 months after LSG.
    1 context sentence
    Summary · context
    Because growth hormone (GH) secretion is reportedly decreased in obese patients, we examined not only the factors associated with the decreased GH secretion but also GH response to the GH-releasing peptide (GHRP)-2-load test before and after laparoscopic gastrectomy (LSG). The study comprised 28 ind…

    In this study, GHRP-2 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-2.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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