In healthy volunteers, serum cortisol did not differ between tubing and direct cosyntropin injection (P = 0.16).
In plain wordsIn healthy volunteers, cortisol did not differ between cosyntropin delivered through tubing and direct injection.
- Peptide
- Cosyntropin
- Outcome
- No significant changeSerum cortisol at 30 minutes
- Study
n = 20
- Comparator
- Direct intravenous injection
- Outcome group
- Diagnostic test performance · Endocrine and hormones
Measurements
- Cortisol
- 20.47 μg/dl
- plastic tube
- Reported variability
- 2.87 μg/dl
- plastic tube
- Cortisol
- 21.62 μg/dl
- direct injection
- Reported variability
- 3.89 μg/dl
- direct injection
- P
- 0.16
- comparison
Source sentences
In vivo, mean 30-min serum cortisol concentrations were 20.47 ± 2.87 and 21.62 ± 3.89 μg/dl in via plastic tube and in via direct intravenous injection tests, respectively, and did not show a significant difference (P = 0.16).
1 context sentence(design, population, supporting numbers)
For the in vivo study, we recruited 20 healthy adult volunteers. Each subject underwent low-dose test via 2.5 cm plastic tube via plastic tube and via direct intravenous injection by a metal syringe via direct intravenous injection, and cortisol responses were determined.
In this study, Cosyntropin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cosyntropin.