In Wistar rats, [d-Lys3]-GHRP‑6 blocked growth hormone release induced by intraduodenal ornithine.
In plain wordsIn rats, the modified GHRP‑6 antagonist blocked growth hormone release induced by ornithine.
- Peptide
- GHRP-6
- Outcome
- DecreaseOrnithine-induced GH release
- Study
ratn: not reported in source
Wistar rats- Outcome group
- Growth hormone and IGF-1 · Endocrine and hormones
Source sentences
GH-releasing activity after intraduodenal administration of l-Orn was blocked by [d-Lys3]-GHRP-6, an antagonist of the ghrelin receptor;
1 context sentence(design, population, supporting numbers)
We found that intraduodenal administration of l-ornithine (l-Orn) stimulates growth hormone (GH) secretion in Wistar rats, and then investigated its mechanism.
In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.