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Study · Measured the body's own peptide · 2017

1 result

Changes in biochemical markers following spinal manipulation-a systematic review and meta-analysis.

Kovanur-Sampath K, Mani R, Cotter J, Gisselman AS, Tumilty S

Musculoskeletal science & practice5 Apr 2017Cited by 38 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelSystematic reviewOther

    In a meta-analysis of trials, spinal manipulation increased the body's own oxytocin levels after the intervention versus control, on low quality evidence.

    In plain wordsIn a review of trials, spinal manipulation raised the body's own oxytocin levels compared with control, based on low quality evidence.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin level after spinal manipulation
    Study

    n: not reported in source

    Comparator
    Control
    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Measurements

    SMD
    −2.61 SMD
    oxytocin levels post-intervention

    Source sentences

    Summary
    There was also a low quality evidence that spinal manipulation is better than control at post-intervention in increasing substance-P (SMD -0.48,95%CI-0.87 to -0.1), neurotensin (SMD -1.8,95%CI-2.56 to -1.04) and oxytocin levels (SMD -2.61,95%CI-3.5to-1.72).
    1 context sentence
    Summary · context
    Electronic databases (n = 10) were searched (from inception till September 2016) and eight trials (325 participants) that met the inclusion criteria were included in the meta-analysis.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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