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Study · Randomized controlled trial · n = 124 · 2017

4 results

Combining oxytocin administration and positive emotion inductions: Examining social perception and analytical performance.

Human LJ, Thorson KR, Woolley JD, Mendes WB

Hormones and behavior21 Mar 2017Cited by 1 (Europe PMC)

PMID28324706 (opens in a new tab)DOI10.1016/j.yhbeh.2017.03.002 (opens in a new tab)PepBankPUB-28324706
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In participants, intranasal oxytocin had no significant main effect on social perception tasks versus placebo.

    In plain wordsIn people in this trial, oxytocin did not change social perception task results compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeMain effect of oxytocin on social perception tasks
    Study

    n = 124

    Comparator
    Placebo
    Analysis
    Exploratory
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    There were no significant main effects of OT condition on social perception tasks, failing to replicate prior research, or on analytical performance.
    1 context sentence
    Summary · context
    Participants (N=124) were randomly assigned to receive an intranasal spray of OT (40IU) or placebo and then viewed one of three videos designed to engender one of the following emotion states: social warmth, pride, or an affectively neutral state.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In participants, intranasal oxytocin had no significant main effect on analytical performance versus placebo.

    In plain wordsIn people in this trial, oxytocin did not change analytical task performance compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeMain effect of oxytocin on analytical performance
    Study

    n = 124

    Comparator
    Placebo
    Analysis
    Exploratory
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    or on analytical performance.
    1 context sentence
    Summary · context
    Participants (N=124) were randomly assigned to receive an intranasal spray of OT (40IU) or placebo and then viewed one of three videos designed to engender one of the following emotion states: social warmth, pride, or an affectively neutral state.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In participants, oxytocin and positive emotion inductions did not interact in their associations with social perception performance.

    In plain wordsIn people in this trial, oxytocin and positive mood inductions did not combine to change social perception performance.

    Peptide
    Oxytocin
    Outcome
    No significant changeOxytocin by emotion induction interaction on social perception
    Study

    n = 124

    Comparator
    Placebo
    Analysis
    Exploratory
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Further, OT condition and positive emotion inductions did not interact with each other in their associations with social perception performance.
    1 context sentence
    Summary · context
    Participants (N=124) were randomly assigned to receive an intranasal spray of OT (40IU) or placebo and then viewed one of three videos designed to engender one of the following emotion states: social warmth, pride, or an affectively neutral state.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In participants, oxytocin versus placebo was associated with worse analytical performance after positive emotion inductions.

    In plain wordsIn people in this trial, after a positive mood induction, oxytocin was linked to worse analytical performance than placebo.

    Peptide
    Oxytocin
    Outcome
    DecreaseOxytocin by emotion induction interaction on analytical performance
    Study

    n = 124

    Comparator
    Placebo
    Analysis
    Exploratory
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    40 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    However, OT condition and positive emotion manipulations did significantly interact in their associations with analytical performance.
    2 context sentences
    Summary · context
    Specifically, combining positive emotion inductions with OT administration was associated with worse analytical performance, with the pride induction no longer benefiting performance and the warmth induction resulting in worse performance.
    Summary · context
    Participants (N=124) were randomly assigned to receive an intranasal spray of OT (40IU) or placebo and then viewed one of three videos designed to engender one of the following emotion states: social warmth, pride, or an affectively neutral state.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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