Serum levels of the body's own LL‑37 were higher in patients with pulmonary tuberculosis than in patients with Gram-positive pneumonia.
In plain wordsPeople with tuberculosis had higher natural LL‑37 levels in blood than people with Gram-positive pneumonia.
- Peptide
- LL-37
- Outcome
- IncreaseSerum LL-37 in tuberculosis versus Gram-positive pneumonia
- Study
n = 60
- Comparator
- Patients with Gram-positive bacteria-induced pneumonia
- Outcome group
- Immune response · Respiratory
Measurements
- Mean serum LL-37
- 13.94 ng/mL
- tuberculosis
- Mean serum LL-37
- 7.87 ng/mL
- Gram-positive pneumonia
Source sentences
The mean (± SEM) LL-37 concentration in patients with TB (13.94±5.13 ng/mL) was significantly higher than that in patients with Gram-positive bacteria-induced pneumonia (7.87±4.58 ng/mL, P=0.00077), in patients with Gram-negative bacteria-induced pneumonia (10.27±3.60 ng/mL, P=0.00730), and in contr…
2 context sentences(design, population, supporting numbers)
Thirty TB patients, 30 patients with pneumonia caused by Gram-positive bacteria, 30 patients with pneumonia caused by Gram-negative bacteria, and 30 healthy control subjects were enrolled in the study.
Serum LL-37 concentration was measured using an enzyme-linked immunosorbent assay (ELISA).
This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.