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Study · Animal study (in vivo) · rat · 2017

2 results

Cerebrolysin reduces mechanical allodynia in a rodent model of peripheral inflammation.

Morales-Medina JC, Griffiths NH, Flores G, Mastranzo VM, Iannitti T

Neuroscience letters26 Jan 2017Cited by 9 (Europe PMC)

PMID28131658 (opens in a new tab)DOI10.1016/j.neulet.2017.01.058 (opens in a new tab)PepBankPUB-28131658
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with CFA-induced inflammation, acute Cerebrolysin reduced mechanical allodynia.

    In plain wordsIn rats with inflammation, Cerebrolysin reduced sensitivity to mechanical pain.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseMechanical allodynia
    Study

    ratn: not reported in source

    CFA-induced peripheral inflammation
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We found that acute administration of Cbl was effective in reducing mechanical allodynia but not peripheral inflammation in the CFA model of inflammatory pain.
    1 context sentence
    Summary · context
    Therefore, we designed a study to test the hypothesis that Cbl would reduce mechanical allodynia in a rat model of peripheral inflammation induced by administration of complete Freund's adjuvant (CFA) in the hind paw.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with CFA-induced inflammation, acute Cerebrolysin did not reduce peripheral inflammation.

    In plain wordsIn rats, Cerebrolysin did not reduce peripheral inflammation.

    Peptide
    Cerebrolysin
    Outcome
    No significant changePeripheral inflammation
    Study

    ratn: not reported in source

    CFA-induced peripheral inflammation
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    We found that acute administration of Cbl was effective in reducing mechanical allodynia but not peripheral inflammation in the CFA model of inflammatory pain.
    1 context sentence
    Summary · context
    Therefore, we designed a study to test the hypothesis that Cbl would reduce mechanical allodynia in a rat model of peripheral inflammation induced by administration of complete Freund's adjuvant (CFA) in the hind paw.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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