In children with cerebral palsy, GMFCS level was significantly lower with Cerebrolysin plus rehabilitation than with rehabilitation alone.
In plain wordsIn children with cerebral palsy, GMFCS level was lower with Cerebrolysin plus rehabilitation than with rehabilitation alone.
- Peptide
- Cerebrolysin
- Outcome
- DecreaseGMFCS level
- Study
n = 50
- Comparator
- Standard rehabilitation therapy
- Outcome group
- Exercise and physical function · Nervous system and cognition
- Studied dose
- 0.1 cc/kg daily for 10 days then weekly · intramuscular · 4 monthsAs given in this study (human).
Measurements
- Mean GMFCS level
- 2.1
- CBL group
- Mean GMFCS level
- 3.16
- Control group
- P value for GMFCS comparison
- < 0.05
- Mean GMFCS level, CBL plus rehabilitation versus control rehabilitation, four months after trial
Source sentences
However, it was significantly lower in the CBL group than in the control group (2.1 vs. 3.16, P < 0.05).
3 context sentences(design, population, supporting numbers)
In this clinical trial study, paediatric patients aged 18-75 months with spastic diplegic or quadriplegic cerebral palsy, who were under rehabilitation therapy, were selected and randomly allocated in control and CBL groups.
Patients in CBL group underwent treatment with standard rehabilitation therapy plus CBL.
The latter was administrated intramuscularly as a single daily dose of 0.1 cc/kg for 10 days and then continued weekly for 4 months.