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Study · Randomized controlled trial · n = 100 · 2017

2 results

Oxytocin modulates third-party sanctioning of selfish and generous behavior within and between groups.

Daughters K, Manstead ASR, Ten Velden FS, De Dreu CKW

Psychoneuroendocrinology3 Dec 2016Cited by 21 (Europe PMC)

PMID28006725 (opens in a new tab)DOI10.1016/j.psyneuen.2016.11.039 (opens in a new tab)PepBankPUB-28006725
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy adults, punishment of selfish investments and back-transfers was higher for in-group members, especially with oxytocin than with placebo.

    In plain wordsIn healthy adults, oxytocin increased punishment of selfish in-group behavior more than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseThird-party punishment of selfish behavior
    Study

    n = 100

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Punishment (reward) was higher for selfish (generous) investments and back-transfers when (i) investors were in-group rather than outgroup, and (ii) trustees were in-group rather than outgroup, especially when (iii) participants received oxytocin rather than placebo.
    1 context sentence
    Summary · context
    Healthy males and females (N=100) self-administered a placebo or 24 IU of oxytocin in a randomized, double-blind, between-subjects design.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy adults, reward of generous investments and back-transfers was higher for in-group members, especially with oxytocin than with placebo.

    In plain wordsIn healthy adults, oxytocin increased reward of generous in-group behavior more than placebo.

    Peptide
    Oxytocin
    Outcome
    IncreaseThird-party reward of generous behavior
    Study

    n = 100

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Mental health and mood
    Studied dose
    24 IUAs given in this study (human).

    Source sentences

    Summary
    Punishment (reward) was higher for selfish (generous) investments and back-transfers when (i) investors were in-group rather than outgroup, and (ii) trustees were in-group rather than outgroup, especially when (iii) participants received oxytocin rather than placebo.
    1 context sentence
    Summary · context
    Healthy males and females (N=100) self-administered a placebo or 24 IU of oxytocin in a randomized, double-blind, between-subjects design.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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