In mice with muscle contusion, macrophage depletion with CL-liposomes decreased MGF expression in the late stage of regeneration.
In plain wordsIn mice, removing macrophages lowered the body's own MGF gene activity late in muscle repair.
- Peptide
- MGF / PEG-MGF
- Outcome
- DecreaseMGF expression after macrophage depletion
- Study
mousen = 112
- Outcome group
- Muscle injury and repair · Musculoskeletal
Source sentences
In addition, CL-liposomes treatment decreased the expression of regulatory factors of muscle regeneration (HGF, uPA, COX-2, IGF-1, MGF, FGF6) and increased the expression of inflammatory cytokines (TGF-β1, TNF-α, IL-1β, RANTES) in the late stage of regeneration.
1 context sentence(design, population, supporting numbers)
One hundred and twelve C57BL/6 mice were randomly divided into muscle contusion and macrophages depleted groups.
This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.