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Study · Measured the body's own peptide · 2017

1 result

Macrophage depletion impairs skeletal muscle regeneration: The roles of regulatory factors for muscle regeneration.

Liu X, Liu Y, Zhao L, Zeng Z, Xiao W, Chen P

Cell biology international18 Jan 2017Cited by 58 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice with muscle contusion, macrophage depletion with CL-liposomes decreased MGF expression in the late stage of regeneration.

    In plain wordsIn mice, removing macrophages lowered the body's own MGF gene activity late in muscle repair.

    Outcome
    DecreaseMGF expression after macrophage depletion
    Study

    mousen = 112

    Outcome group
    Muscle injury and repair · Musculoskeletal

    Source sentences

    Summary
    In addition, CL-liposomes treatment decreased the expression of regulatory factors of muscle regeneration (HGF, uPA, COX-2, IGF-1, MGF, FGF6) and increased the expression of inflammatory cytokines (TGF-β1, TNF-α, IL-1β, RANTES) in the late stage of regeneration.
    1 context sentence
    Summary · context
    One hundred and twelve C57BL/6 mice were randomly divided into muscle contusion and macrophages depleted groups.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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