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Study · Randomized controlled trial · n = 40 · 2017

3 results

Oxytocin Reduces Face Processing Time but Leaves Recognition Accuracy and Eye-Gaze Unaffected.

Hubble K, Daughters K, Manstead AS, Rees A, Thapar A, van Goozen SH

Journal of the International Neuropsychological Society : JINS21 Nov 2016Cited by 30 (Europe PMC)

PMID27866504 (opens in a new tab)DOI10.1017/s1355617716000886 (opens in a new tab)PepBankPUB-27866504
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin had no effect on facial emotion recognition accuracy versus placebo.

    In plain wordsIn healthy men, oxytocin spray did not change how accurately they recognised facial emotions, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEmotion recognition accuracy
    Study

    n = 40

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Although OXT had no effect on emotion recognition accuracy
    1 context sentence
    Summary · context
    In a double-blind, within-subjects, randomized control experiment, 40 healthy male participants received 24 IU intranasal OXT and placebo in two identical experimental sessions separated by a 2-week interval.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin shortened face processing time across emotions versus placebo, a marginally significant effect.

    In plain wordsIn healthy men, oxytocin spray made face processing a little faster than placebo did, though the result was only borderline.

    Peptide
    Oxytocin
    Outcome
    DecreaseFace processing time
    Study

    n = 40

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    recognition performance was improved because face processing was faster across emotions under the influence of OXT.
    2 context sentences
    Summary · context
    This effect was marginally significant (p<.06).
    Summary · context
    In a double-blind, within-subjects, randomized control experiment, 40 healthy male participants received 24 IU intranasal OXT and placebo in two identical experimental sessions separated by a 2-week interval.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In healthy men, intranasal oxytocin had no effect on eye-gaze patterns when viewing static emotional faces versus placebo.

    In plain wordsIn healthy men, oxytocin spray did not change where they looked on emotional faces, compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeEye-gaze patterns
    Study

    n = 40

    Comparator
    Placebo
    Outcome group
    Social behavior and cognition · Nervous system and cognition
    Studied dose
    24 IU · intranasalAs given in this study (human).

    Source sentences

    Summary
    Consistent with a previous study using dynamic stimuli, OXT had no effect on eye-gaze patterns when viewing static emotional faces and this was not related to recognition accuracy or face processing time.
    1 context sentence
    Summary · context
    In a double-blind, within-subjects, randomized control experiment, 40 healthy male participants received 24 IU intranasal OXT and placebo in two identical experimental sessions separated by a 2-week interval.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:49 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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