Socioeconomic Disparities in Childhood Obesity Risk: Association With an Oxytocin Receptor Polymorphism.

Bush NR, Allison AL, Miller AL, Deardorff J, Adler NE, Boyce WT

JAMA pediatrics1 Jan 2017Cited by 33 (Europe PMC)

PMID27842184DOI10.1001/jamapediatrics.2016.2332PepBankPUB-27842184

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

01HumanNot a test of Oxytocin aloneObservational studyOther
In children who carry the A allele of the oxytocin receptor polymorphism rs53576, higher family socioeconomic status was associated with lower BMI z score.
In plain wordsIn children with the A allele of an oxytocin receptor gene variant, higher family socioeconomic status was linked to lower BMI.
Peptide
Oxytocin
Outcome
DecreaseSES and child BMI z score in OXTR A allele carriers
Study
n = 97
Outcome group
Body weight · Metabolic and weight
Measurements
Decrease in BMIz per 1-SD SES
0.28 BMIz
A allele carriers
Source sentences
Summary
Among 97 A allele carriers, a 1-SD increase in SES was associated with a decrease in BMIz of 0.28 (95% CI, -0.47 to -0.09)
1 context sentence(design, population, supporting numbers)
Summary · context
From the original community sample of 338 typically developing children, participants were 186 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age range, 9.4-11.3 years; 93 females [50%]) who had sufficient data at the follow-up assessment for inclusion in this study.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2784218401
02HumanNot a test of Oxytocin aloneObservational studyOther
In children who carry the A allele of the oxytocin receptor polymorphism rs53576, higher family socioeconomic status was associated with lower triceps skinfold thickness.
In plain wordsIn children with the A allele of an oxytocin receptor gene variant, higher family socioeconomic status was linked to thinner skinfolds.
Peptide
Oxytocin
Outcome
DecreaseSES and child skinfold thickness in OXTR A allele carriers
Study
n = 97
Outcome group
Body weight · Metabolic and weight
Measurements
Decrease in skinfold thickness per 1-SD SES
0.95 mm
A allele carriers
Source sentences
Summary
a decrease in skinfold thickness of 0.95 (95% CI, -1.77 to -0.12) mm
1 context sentence(design, population, supporting numbers)
Summary · context
From the original community sample of 338 typically developing children, participants were 186 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age range, 9.4-11.3 years; 93 females [50%]) who had sufficient data at the follow-up assessment for inclusion in this study.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2784218402
03HumanNot a test of Oxytocin aloneObservational studyOther
In children with the GG genotype of the oxytocin receptor polymorphism rs53576, socioeconomic status was unrelated to BMI z score.
In plain wordsIn children with the GG version of an oxytocin receptor gene variant, family socioeconomic status was not linked to BMI.
Peptide
Oxytocin
Outcome
No significant changeSES and child BMI z score in OXTR GG genotype
Study
n = 89
Outcome group
Body weight · Metabolic and weight
Source sentences
Summary
Socioeconomic status was unrelated to BMIz (95% CI, -0.21 to 0.26) or skinfold thickness (95% CI, -0.42 to 1.45) for 89 GG genotyped children.
1 context sentence(design, population, supporting numbers)
Summary · context
From the original community sample of 338 typically developing children, participants were 186 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age range, 9.4-11.3 years; 93 females [50%]) who had sufficient data at the follow-up assessment for inclusion in this study.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2784218403
04HumanNot a test of Oxytocin aloneObservational studyOther
In children with the GG genotype of the oxytocin receptor polymorphism rs53576, socioeconomic status was unrelated to triceps skinfold thickness.
In plain wordsIn children with the GG version of an oxytocin receptor gene variant, family socioeconomic status was not linked to skinfold thickness.
Peptide
Oxytocin
Outcome
No significant changeSES and child skinfold thickness in OXTR GG genotype
Study
n = 89
Outcome group
Body weight · Metabolic and weight
Source sentences
Summary
Socioeconomic status was unrelated to BMIz (95% CI, -0.21 to 0.26) or skinfold thickness (95% CI, -0.42 to 1.45) for 89 GG genotyped children.
1 context sentence(design, population, supporting numbers)
Summary · context
From the original community sample of 338 typically developing children, participants were 186 socioeconomically and racially/ethnically diverse children (mean age, 10.3 years; age range, 9.4-11.3 years; 93 females [50%]) who had sufficient data at the follow-up assessment for inclusion in this study.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.
Report a problemFND-2784218404

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
11 Oct 2026, 01:30 UTC
Study results updated
Version 1
9 Oct 2026, 02:50 UTC
First added · source update from Europe PMC

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